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Key Documents

F9108

Sigma-Aldrich

5-Fluoroindole

98%

Sinonimo/i:

NSC 88613

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali


About This Item

Formula empirica (notazione di Hill):
C8H6FN
Numero CAS:
Peso molecolare:
135.14
Beilstein:
112350
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

Livello qualitativo

Saggio

98%

Punto di fusione

45-48 °C (lit.)

Stringa SMILE

Fc1ccc2[nH]ccc2c1

InChI

1S/C8H6FN/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5,10H
ODFFPRGJZRXNHZ-UHFFFAOYSA-N

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Applicazioni

  • Reactant for preparation of 5-HT6 receptor ligands
  • Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
  • Reactant for preparation of antitumor agents
  • Reactant for preparation of antibacterial agents
  • Reactant for preparation of immunosuppressive agents
  • Reactant for preparation of Sodium-Dependent Glucose Co-transporter 2 (SGLT2) Inhibitors for the Management of Hyperglycemia in Diabetes
  • Reactant for preparation of Myeloperoxidase Inhibitors
  • Reactant for preparation of Potent Selective Serotonin Reuptake Inhibitors

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

230.0 °F - closed cup

Punto d’infiammabilità (°C)

110 °C - closed cup

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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Certificati d'analisi (COA)

Lot/Batch Number

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A L Palombella et al.
Plant physiology, 117(2), 455-464 (1998-06-25)
We report the isolation of a Chlamydomonas reinhardtii cDNA that encodes the beta-subunit of tryptophan synthase (TSB). This cDNA was cloned by functional complementation of a trp-operon-deleted strain of Escherichia coli. Hybridization analysis indicated that the gene exists in a
Steffen P Graether et al.
Journal of magnetic resonance (San Diego, Calif. : 1997), 178(1), 65-71 (2005-10-04)
We show that it is feasible to use a minicoil for solid-state 19F 1H NMR experiments that has short pulse widths, good RF homogeneity, and excellent signal-to-noise for small samples while using low power amplifiers typical to liquid-state NMR. The
Nicholas A Magnus et al.
Organic letters, 12(16), 3700-3703 (2010-08-14)
A practical synthesis of the glycogen synthase kinase-3 (GSK3) inhibitor bisarylmaleimide 1 has been accomplished employing Pictet-Spengler methodology to access the indole 7-position in preparing the benzodiazepine tricyclic fragment. A seven-step linear sequence that starts with commercially available 5-fluoroindole 7
Peter B Crowley et al.
Chemical communications (Cambridge, England), 48(86), 10681-10683 (2012-09-25)
Fluorine-containing amino acids are valuable probes for the biophysical characterization of proteins. Current methods for (19)F-labeled protein production involve time-consuming genetic manipulation, compromised expression systems and expensive reagents. We show that Escherichia coli BL21, the workhorse of protein production, can
A J Barczak et al.
Genetics, 140(1), 303-313 (1995-05-01)
A study of the biochemical genetics of the Arabidopsis thaliana tryptophan synthase beta subunit was initiated by characterization of mutants resistant to the inhibitor 5-fluoroindole. Thirteen recessive mutations were recovered that are allelic to trp2-1, a mutation in the more

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