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Poly(2-ethyl-2-oxazoline) 5-7 cSt

Name: Poly(2-ethyl-2-oxazoline) 5-7 cSt
Brand: ALDRICH

Sinonimo/i:

Poly(2-ethyl-2-oxazoline), PEOX, POx, PetOx, poly 2-ethyloxazoline, polyethyloxazoline

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About This Item

Formula condensata:

[-N(COC₂H₅)CH₂CH₂-]_n

Numero CAS:

25805-17-8

Numero MDL:

MFCD00134377

Codice UNSPSC:

12162002

ID PubChem:

329755635

NACRES:

NA.23

Forma fisica

solid

Livello qualitativo

200

PM

average M_w ~50,000

Indice di rifrazione

n20/D 1.52

Viscosità

5-7 cSt, 10 % in water(100 °F)

Temp. transizione

softening point 110-120 °C (Vicat, ASTM D 1525-82)
T_g 69-71 °C

Densità

1.14 g/mL at 25 °C (lit.)

Ind. polidispersione

3‑4

InChI

1S/C5H9NO/c1-2-5-6-3-4-7-5/h2-4H2,1H3
NYEZZYQZRQDLEH-UHFFFAOYSA-N

Categorie correlate

Polimeri idrofili

Applicazioni

This Poly(2-ethyl-2-oxazoline) polymer is amorphous and water soluble with good temperature stability. Jordan and coworkers showed biocompatibility, no accumulation in tissue, and rapid clearance from the bloodstream. End-group modified poly(2-ethyl-2-oxazoline)s have been conjugated to peptides, and were shown as versatile alternatives to poly(ethylene glycol) (PEG) for both protein and small drug conjugation.

Potential substitute for poly(vinyl alcohol) and poly(vinyl pyrrolidone). Adhesion promoter in coatings. Heat sealing and remoistenable hot-melt adhesive

Caratteristiche e vantaggi

Nonionic, water-soluble thermoplastic. Better heat stability than poly(vinyl alcohol). Good melt flow, shear stability and Newtonian characteristics. Water is a room temperature Theta solvent.

Stato fisico

N-propionyl substituted linear polyethylenimine

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Paclitaxel and iron oxide loaded multifunctional nanoparticles for chemotherapy, fluorescence properties, and magnetic resonance imaging.

Yung-Chu Chen et al.

Journal of biomedical materials research. Part A, 100(5), 1279-1292 (2012-03-01)

The multifunctional nanoparticles constructed from triphenylamine-poly(lactide-co-glycolide)-poly(ethyleneglycol)-poly(lactide-co-glycolide) (TPA-PEP) and folate-poly(2-ethyl-2oxazoline)-poly(D,L-lactide) (folate-PEOz-PLA) were developed in this study. Iron oxide nanoparticles (IOP) and paclitaxel (PTX) were coencapsulated in the nanoparticles with diameter less than 200 nm. The drug-loaded nanoparticles emit fluorescence peak at

Electrically erodible polymer gel for controlled release of drugs.

I C Kwon et al.

Nature, 354(6351), 291-293 (1991-11-28)

New controlled drug-delivery systems are being explored to overcome the disadvantages of conventional dosage forms. For example, stimulated drug-delivery has been used to overcome the tolerance problems that occur with a constant delivery rate, to mimic the physiological pattern of

Polymeric micelles with a pH-responsive structure as intracellular drug carriers.

Chau-Hui Wang et al.

Journal of controlled release : official journal of the Controlled Release Society, 108(1), 140-149 (2005-09-27)

Polymeric micelles based on poly(L-lactide)-b-poly(2-ethyl-2-oxazoline)-b-poly(L-lactide) (PLLA-PEOz-PLLA) ABA triblock copolymers were designed as intracellular drug carriers. The PLLA-PEOz-PLLA micelles adopt a "flower-like" arrangement with A-blocks at the core and a B-block on the shell under neutral condition. The deformation of the

New amphiphilic poly(2-ethyl-2-oxazoline)/ poly(L-lactide) triblock copolymers.

Chau-Hui Wang et al.

Biomacromolecules, 4(6), 1487-1490 (2003-11-11)

A new series of cationic, thermo-sensitive, and biodegradable poly(L-lactide)-poly(2-ethyl-2-oxazoline)-poly(L-lactide) (PLLA-PEOz-PLLA) triblock copolymers were synthesized by ring-opening polymerization. With increasing molecular weight and crystallinity of hydrophobic PLLA blocks, the critical micellization concentrations (CMC) occurred at lower concentration. The PLLA-PEOz-PLLA aqueous solution

Non-viral-mediated gene therapy approaches for bone repair.

S R Winn et al.

Orthodontics & craniofacial research, 8(3), 183-190 (2005-07-19)

Bone repair strategies continue to be developed for alternatives to autografting, allogeneic implants of banked bone, and other bone substitutes. Efforts have included the delivery of potent growth and/or differentiation factors and the use of gene therapy. For bone regeneration

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