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189898

Sigma-Aldrich

Methylmagnesium bromide solution

3.0 M in diethyl ether

Sinonimo/i:

Bromomethylmagnesium

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About This Item

Formula condensata:
CH3MgBr
Numero CAS:
75-16-1
Peso molecolare:
119.24
Beilstein:
3535220
Numero MDL:
MFCD00000041
Codice UNSPSC:
12352111
ID PubChem:
24851403
NACRES:
NA.22

Livello qualitativo

200

Impiego in reazioni chimiche

reaction type: Grignard Reaction

Concentrazione

3.0 M in diethyl ether

Densità

1.035 g/mL at 25 °C

Stringa SMILE

C[Mg]Br

InChI

1S/CH3.BrH.Mg/h1H3;1H;/q;;+1/p-1
AVFUHBJCUUTGCD-UHFFFAOYSA-M

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Categorie correlate

Descrizione generale

Methylmagnesium bromide solution, also known as bromomethylmagnesium, is both a Lewis acid and nucleophile. It is commonly used as a grignard reagent in organic synthesis reactions.

Applicazioni

Methylmagnesium bromide solution (3M in diethyl ether) is used to synthesize:
  • 3S-(Boc-amino)-2,4-dimethyl-2-pentanol and methyl tert-butyl (S)-sulfoxide.
  • Methyl potassium polyimide (K-PIM-1) (MeMgBr).
  • 3(4R)-{3(2R,3S)-[4′-(1′-triphenylmethyl)imidazole]-2-bromo-1-oxobutyl)-4-phenyl2-oxazolidinone
  • Benzyl 2-(2-oxopropyl)piperidine-1-carboxylate
  • (R*, R*) 1-[1-(1-phenylethyl)pyrrolidin-2-yl]propan-2-one)

Confezionamento

The 25 mL Sure/Seal™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.
View returnable container options.

Note legali

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Avvertenze

Danger

Indicazioni di pericolo

H224,H260,H302,H314,H336

Classi di pericolo

Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 1 - Skin Corr. 1B - STOT SE 3 - Water-react 1

Organi bersaglio

Central nervous system

Rischi supp

EUH019

Codice della classe di stoccaggio

4.3 - Hazardous materials which set free flammable gases upon contact with water

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

-40.0 °F - closed cup

Punto d’infiammabilità (°C)

-40 °C - closed cup

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Certificati d'analisi (COA)

Lot/Batch Number
SHBN4763
SHBM8188
SHBM8112
SHBM0873
SHBL3954

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