Passa al contenuto
Merck
Tutte le immagini(3)

Key Documents

View All Documentation

104493

Sigma-Aldrich

Chloroacetyl chloride

98%

Sinonimo/i:

Chloroacetic chloride

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(3)

About This Item

Formula condensata:
ClCH2COCl
Numero CAS:
79-04-9
Peso molecolare:
112.94
Beilstein:
605439
Numero CE:
201-171-6
Numero MDL:
MFCD00000725
Codice UNSPSC:
12352100
ID PubChem:
24846647
NACRES:
NA.22

Densità del vapore

3.9 (vs air)

Livello qualitativo

200

Tensione di vapore

60 mmHg ( 41.5 °C)

Saggio

98%

Indice di rifrazione

n20/D 1.453 (lit.)

P. eboll.

105-106 °C (lit.)

Punto di fusione

−22 °C (lit.)

Densità

1.418 g/mL at 25 °C (lit.)

Gruppo funzionale

acyl chloride
chloro

Stringa SMILE

ClCC(Cl)=O

InChI

1S/C2H2Cl2O/c3-1-2(4)5/h1H2
VGCXGMAHQTYDJK-UHFFFAOYSA-N

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Categorie correlate

Descrizione generale

Chloroacetyl chloride is used as a chlorinating agent, acylating agent, precursor to monochloroketene, and as a building block for cyclization.

Chloroacetyl chloride causes the acylation of cyano-pyrazoline during the synthesis of secondary amine-substituted cyano-pyrazoline derivatives.

Applicazioni

Chloroacetyl chloride can be used for chloroacetylation and chemical modification of poly(glycidyl methacrylate). Chloroacetyl chloride was used to study the in vitro metabolism of chloroacetamide herbicides by rat and human liver microsomes. Chloroacetyl chloride was used in the synthesis of some novel quinoline derivatives having antileishmanial activity.

Avvertenze

Danger

Indicazioni di pericolo

H301 + H311 + H331,H314,H372,H400

Classi di pericolo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1A - STOT RE 1

Organi bersaglio

Lungs

Rischi supp

EUH014,EUH029

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

212.0 °F - closed cup

Punto d’infiammabilità (°C)

100 °C - closed cup

Dispositivi di protezione individuale

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
MKCQ7793
MKCP3299
MKCL6859
STBJ3969
MKCK6340

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 8

1 of 8

Chloroacetyl chloride-2-13C 99 atom % 13C

Sigma-Aldrich

604097

Chloroacetyl chloride-2-13C

Diethylamine ≥99.5%

Sigma-Aldrich

471216

Diethylamine

Chloroacetic anhydride 95%

Sigma-Aldrich

215163

Chloroacetic anhydride

L-Prolinamide 98%

Sigma-Aldrich

287059

L-Prolinamide

Chloroacetic acid ACS reagent, ≥99.0%

Sigma-Aldrich

402923

Chloroacetic acid

2-Chloropropionyl chloride 97%

Sigma-Aldrich

157139

2-Chloropropionyl chloride

Chloroacetyl isocyanate ≥95%

Sigma-Aldrich

259322

Chloroacetyl isocyanate

1-Phenyl-2-propyn-1-ol 98%

Sigma-Aldrich

226610

1-Phenyl-2-propyn-1-ol

Jin Hee Ahn et al.
Bioorganic & medicinal chemistry letters, 14(17), 4461-4465 (2004-09-11)
A new series of cyano-pyrazoline derivatives with secondary amine at P-2 site was synthesized through achiral and chiral synthetic methods and evaluated for their ability to inhibit dipeptidyl peptidase IV (DP-IV). Compound 5i revealed good in vivo efficacy (ED50: 4.1
Niranjan P Sahu et al.
Bioorganic & medicinal chemistry, 10(6), 1687-1693 (2002-04-09)
Some novel quinoline derivatives were prepared and tested for antileishmanial activity. 2-(2-Methylquinolin-4-ylamino)-N-phenylacetamide (2) was found to be significantly more active than the standard antileishmanial drug sodium antimony gluconate (SAG) in reducing the parasite load both in the spleen and liver
S Coleman et al.
Environmental health perspectives, 108(12), 1151-1157 (2001-01-03)
Acetochlor [2-chloro-N-(ethoxymethyl)-N-(2-ethyl-6-methyl-phenyl)-acetamide], alachlor [N-(methoxymethyl)-2-chloro-N-(2, 6-diethyl-phenyl)acetamide], butachlor [N-(butoxymethyl)-2-chloro-N-(2,6-diethyl-phenyl)acetamide], and metolachlor [2-chloro-N-(2-ethyl-6-methylphenyl)-N-(2-methoxy-1-methylethyl) acetamide] are pre-emergent herbicides used in the production of agricultural crops. These herbicides are carcinogenic in rats: acetochlor and alachlor cause tumors in the nasal turbinates, butachlor causes stomach tumors
Kenawy el-R et al.
Journal of controlled release : official journal of the Controlled Release Society, 50(1-3), 145-152 (1998-08-01)
Polymers with antibacterial activity have been synthesized by chemical modification of poly(glycidyl methacrylate). The glycidyl methacrylate was polymerized by the free radical polymerization technique. The poly(glycidyl methacrylate) was hydrolyzed and was chloroacetylated using chloroacetyl chloride. The chloroacetylated product was modified
[Hygienic standardization of monochloracetic acid chloranhydride in the air of the work area].
A L Germanova et al.
Gigiena truda i professional'nye zabolevaniia, (10)(10), 56-57 (1988-10-01)
Visualizza tutti i documenti correlati

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.