D80002

DCC

99%

• Synonyme(s) : N,N′-Dicyclohexylcarbodiimide
• Formule linéaire : C₆H₁₁N=C=NC₆H₁₁
• Numéro CAS: 538-75-0
• Poids moléculaire : 206.33
• Numéro Beilstein : 610662
• Numéro CE : 208-704-1
• Numéro MDL: MFCD00011659
• Code UNSPSC : 12352111
• ID de substance PubChem : 24894174
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 200
• Pureté: 99%
• Forme: solid
• Capacité de réaction: reaction type: Coupling Reactions
• Point d'ébullition: 122-124 °C/6 mmHg (lit.)
• Pf: 34-35 °C (lit.)
• Chaîne SMILES: C1CCC(CC1)N=C=NC2CCCCC2
• InChI: 1S/C13H22N2/c1-3-7-12(8-4-1)14-11-15-13-9-5-2-6-10-13/h12-13H,1-10H2
• Clé InChI: QOSSAOTZNIDXMA-UHFFFAOYSA-N
• Informations sur le gène: human ... EPHX2(2053) ; mouse ... Ephx2(13850)

Description

Description générale

DCC is the acronym for N,N′-dicyclohexylcarbodiimide. In peptide synthesis, it is utilized for the activation of carboxyl group. The structure of DCC has been analyzed based on IR and Raman spectral data. It mediates the esterification of poly(vinyl alcohol) with free levulinic acid to form poly(vinyl alcohol-co-vinyl levulinate).

Application

Carboxy group activating reagent for peptide synthesis.

DCC has been used in the preparation of titanate nanotubes-phthalocyanine(TiONts-Pc) nanohybrids and 7-((tert-butyldimethylsilyl)oxy)hepta-2,4-diyn-1-yl propynoate.

DCC may be used to promote the esterification of
7-((tert-butyldimethylsilyl)oxy)hepta-2,4-diyn-1-ol with propiolic acid to form 7-((tert-butyldimethylsilyl)oxy)hepta-2,4-diyn-1-yl propynoate.
It can also used to synthesize:

• 1,3-Thiazetedine derivatives via [2+2] cycloaddition with 2-phenylethenyl- and 2-(4-nitrophenyl)ethenyl isothiocyanates.
• 1,3,5-Oxadiazine-4-thiones via [4+2] cycloaddition with benzoyl isothiocyanates.
• Sterically hindered 1,3,4-oxadiazole derivatives by reacting with (N-isocyanimino)triphenylphosphorane in the presence of aromatic (or heteroaromatic) carboxylic acids.

Informations sur la sécurité

• Pictogrammes: GHS06,GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H302,H311,H317,H318
• Conseils de prudence: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1
• Code de la classe de stockage: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 235.4 °F - closed cup
• Point d'éclair (°C): 113 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges