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Merck

PHR1556

Supelco

4-Methyl-2-pentanon

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

Isobutylmethylketon, Isopropylaceton, MIBK, Methylisobutylketon

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About This Item

Lineare Formel:
(CH3)2CHCH2COCH3
CAS-Nummer:
Molekulargewicht:
100.16
Beilstein:
605399
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

Agentur

traceable to USP 1430203

Dampfdichte

3.5 (vs air)

Analysenzertifikat (CofA)

current certificate can be downloaded

Selbstzündungstemp.

840 °F

Expl.-Gr.

1.2-8 %, 93 °F

Verpackung

ampule of 3x1.2 mL each

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Brechungsindex

n20/D 1.395 (lit.)

bp

117-118 °C

mp (Schmelzpunkt)

−80 °C (lit.)

Dichte

0.801 g/mL at 25 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-30°C

SMILES String

CC(C)CC(C)=O

InChI

1S/C6H12O/c1-5(2)4-6(3)7/h5H,4H2,1-3H3

InChIKey

NTIZESTWPVYFNL-UHFFFAOYSA-N

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Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Anwendung

Methyl Isobutyl Ketone may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAB9508 in the slot below. This is an example certificate only and may not be the lot that you receive.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Inhalation - Carc. 2 Inhalation - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Zielorgane

Central nervous system

Zusätzliche Gefahrenhinweise

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 1

Flammpunkt (°F)

57.2 °F - closed cup

Flammpunkt (°C)

14 °C - closed cup


Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

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Some applications of state-of-the-art capillary gas chromatography in the pharmaceutical industry
Sandra P, et al.
TrAC, Trends in Analytical Chemistry, 21(9-10), 662-671 (2002)
Screening methods for impurities in multi-sourced fluoxetine hydrochloride drug substances and formulations
Wirth DD, et al.
Chromatographia, 46(9-10), 511-511 (1997)
Vincent W Chen et al.
Optics express, 22(10), 12316-12326 (2014-06-13)
Cuboid-shaped organic microcavities containing a pyrromethene laser dye and supported upon a photonic crystal have been investigated as an approach to reducing the lasing threshold of the cavities. Multiphoton lithography facilitated fabrication of the cuboid cavities directly on the substrate
Maria V Vavoura et al.
Molecules (Basel, Switzerland), 20(2), 1922-1940 (2015-01-30)
Volatile compounds, physicochemical and sensory attributes of four sweet cherry cultivars (Canada giant, Ferrovia, Lapins and Skeena) grown in Northern Greece were determined. Eighteen volatile compounds were identified and semi-quantified in cherries using solid phase micro extraction in combination with
Navideh Sadoughi et al.
Journal of agricultural and food chemistry, 63(11), 2877-2885 (2015-02-24)
An optimized method for the quantitation of volatile compounds responsible for off-aromas, such as earthy odors, found in wine and grapes was developed. The method involved a fast and simple headspace solid-phase microextraction-gas chromatography-mass spectrometry (HS-SPME-GC-MS) for simultaneous determination of

Protokolle

Separation of 4-Methyl-2-pentanone; Dimethyl disulfide; Hexanal; 3-Methylpentane; Acetone

GC Analysis of Class 3 Residual Solvents on SUPELCOWAX® 10

US EPA Method 8260: GC Analysis of Volatiles on SPB®-624 after Purge & Trap using "K" Trap, Fast GC Analysis

Verwandter Inhalt

Butyl methyl ether; Acetic acid; 2-Butanone; Ethyl acetate; Tetrahydrofuran; 1-Butanol; Isopropyl acetate; Heptane; Propyl acetate; 3-Methylbutanol; 4-Methyl-2-pentanone; Isobutyl acetate; Butyl acetate; Dimethyl sulfoxide; Anisole; Cumene

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