1357056

Leflunomide Related Compound B

United States Pharmacopeia (USP) Reference Standard

• Sinônimo(s): 2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide
• Fórmula empírica (Notação de Hill): C₁₂H₉F₃N₂O₂
• Número CAS: 108605-62-5
• Peso molecular: 270.21
• Número MDL: MFCD00910058
• Código UNSPSC: 41116107
• ID de substância PubChem: 329750239
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• família API: leflunomide
• fabricante/nome comercial: USP
• aplicação(ões): pharmaceutical (small molecule)
• formato: neat
• cadeia de caracteres SMILES: O=C(/C(C#N)=C(O)/C)NC1=CC=C(C(F)(F)F)C=C1
• InChI: 1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-
• chave InChI: UTNUDOFZCWSZMS-YFHOEESVSA-N
• Informações sobre genes: human ... DHODH(1723)

Descrição

Descrição geral

Leflunomide Related Compound B (2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide is a malononitrilamide which is a water soluble metabolite of Leflunomide. It is considered as a noncompetitive inhibitor of dihydro-orotate dehydrogensae. This metabolite has been reported to initially target activated lymphocytes.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H302
• Classificações de perigo: Acute Tox. 4 Oral
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable