1302101

Guanfacine hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Sinônimo(s): N (Aminoiminomethyl)-2,6-dichlorobenzeneacetamide
• Fórmula empírica (Notação de Hill): C₉H₉Cl₂N₃O · HCl
• Número CAS: 29110-48-3
• Peso molecular: 282.55
• Número MDL: MFCD00798230
• Código UNSPSC: 41116107
• ID de substância PubChem: 329749977
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• família API: guanfacine
• fabricante/nome comercial: USP
• aplicação(ões): pharmaceutical (small molecule)
• formato: neat
• cadeia de caracteres SMILES: Cl.NC(=N)NC(=O)Cc1c(Cl)cccc1Cl
• InChI: 1S/C9H9Cl2N3O.ClH/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13;/h1-3H,4H2,(H4,12,13,14,15);1H
• chave InChI: DGFYECXYGUIODH-UHFFFAOYSA-N
• Informações sobre genes: human ... ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

• Reduction of Anxiety-related Reactivity in Primates: Guanfacine hydrochloride mediates anxiety-related reactivity and reduces associated agonistic behavior in two pigtail macaques, showcasing its potential for managing stress and aggression in clinical and veterinary settings (Hopper et al., 2024).


• Enhanced Analgesia for Surgical Procedures: The synergistic interaction of guanfacine with lidocaine enhances cutaneous analgesia, indicating its utility in improving pain management strategies, particularly in surgical environments (Chou et al., 2024).

Ações bioquímicas/fisiológicas

α-2 noradrenergic receptor agonist.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Informações de segurança

• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable