1272000

Flucytosine

United States Pharmacopeia (USP) Reference Standard

• Sinônimo(s): 5-Fluorocytosine, 4-amino-5-fluoro-2(1H)-pyrimidinone, Flucytosine
• Fórmula empírica (Notação de Hill): C₄H₄FN₃O
• Número CAS: 2022-85-7
• Peso molecular: 129.09
• Beilstein: 127285
• Número MDL: MFCD00006035
• Código UNSPSC: 41116107
• ID de substância PubChem: 329749852
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• família API: flucytosine
• fabricante/nome comercial: USP
• pf: 298-300 °C (dec.) (lit.)
• aplicação(ões): pharmaceutical (small molecule)
• Formato: neat
• cadeia de caracteres SMILES: NC1=NC(=O)NC=C1F
• InChI: 1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9)
• chave InChI: XRECTZIEBJDKEO-UHFFFAOYSA-N

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Flucytosine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Flucytosine Capsules
• Flucytosine Compounded Oral Suspension

Ações bioquímicas/fisiológicas

Nucleoside analog that has antifungal activities. 5-FC is deaminated by cytosine deaminase to product 5-fluorouracil, resulting in RNA miscoding. 5-Fluorocytosine inhibits DNA and RNA synthesis and interferes with ribosomal protein synthesis.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS08
• Palavra indicadora: Warning
• Frases de perigo: H361
• Declarações de precaução: P280
• Classificações de perigo: Repr. 2
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable