1078700

Buprenorphine hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Sinônimo(s): [5α,7α(S)]-17-(Cyclopropylmethyl)-α-(1,1-dimethylethyl)4,5-epoxy-18,19-dihydo-3-hydroxy-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanol hydrochloride
• Fórmula empírica (Notação de Hill): C₂₉H₄₁NO₄ · HCl
• Número CAS: 53152-21-9
• Peso molecular: 504.10
• Número MDL: MFCD00084836
• Código UNSPSC: 41116107
• ID de substância PubChem: 329749160
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• família API: buprenorphine
• fabricante/nome comercial: USP
• controle de medicamentos: USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)
• aplicação(ões): pharmaceutical (small molecule)
• Formato: neat
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: Cl[H].CO[C@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]4Cc5ccc(O)c6O[C@@H]2[C@]3(CCN4CC7CC7)c56
• InChI: 1S/C29H41NO4.ClH/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28;/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3;1H/t20-,21-,24-,26+,27-,28+,29-;/m1./s1
• chave InChI: UAIXRPCCYXNJMQ-RZIPZOSSSA-N

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Buprenorphine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Buprenorphine and Naloxone Sublingual Tablets
• Buprenorphine Compounded Buccal Solution, Veterinary
• Buprenorphine Hydrochloride

Ações bioquímicas/fisiológicas

Agonist at ORL1 receptors; antagonist or partial agonist at μ, κ, and δ opioid receptors.

Full agonist at ORL1 receptors, antagonist or partial agonist at μ, κ, and δ opioid receptors.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS08,GHS07
• Palavra indicadora: Warning
• Frases de perigo: H302,H361
• Declarações de precaução: P280 - P301 + P312 + P330
• Classificações de perigo: Acute Tox. 4 Oral - Repr. 2
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable