569253-U
Discovery® HS C18 (3 µm) HPLC Columns
L × I.D. 5 cm × 2.1 mm, HPLC Column
Sinônimo(s):
Discovery RP18 HPLC Column
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About This Item
Código UNSPSC:
41115700
eCl@ss:
32110501
NACRES:
SB.52
Produtos recomendados
product name
Coluna de HPLC C18 Discovery® HS, 3 μm particle size, L × I.D. 5 cm × 2.1 mm
Materiais
stainless steel column
Agency
suitable for USP L1
linha de produto
Discovery®
Características
endcapped
fabricante/nome comercial
Discovery®
embalagem
1 ea of
Extensão da rotulagem
20% Carbon loading
Parâmetros
≤70 °C temp. range
400 bar pressure (5801 psi)
técnica(s)
HPLC: suitable
LC/MS: suitable
C × D.I.
5 cm × 2.1 mm
área da superfície
300 m2/g
cobertura de superfície
3.2 μmol/m2
Impurezas
<10 ppm metals
matriz
silica gel, high purity, spherical particle platform
fully porous particle
Grupo ativo da matriz
C18 (octadecyl) phase
tamanho de partícula
3 μm
tamanho de poro
120 Å
operating pH range
2-8
aplicação(ões)
food and beverages
técnica de separação
reversed phase
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Descrição geral
Discovery® HS C18 HPLC column (L × I.D. 5 cm × 2.1 mm) is commonly found to be stable under acidic and basic conditions.
Aplicação
- Stereoselective separation of omeprazole and 5-hydroxy-omeprazole using dried plasma spots and a heart-cutting 2D-LC approach for accurate CYP2C19 phenotyping: This research utilizes the Discovery® HS C18 HPLC column for its superior selectivity and sensitivity in pharmacogenetic studies, providing vital data for personalized medicine approaches in drug metabolism (Abouir et al., 2024).
- A stability indicating RP-HPLC method for determination of the COVID-19 drug molnupiravir applied using nanoformulations in permeability studies: This study highlights the effectiveness of the Discovery® HS C18 column in the rapid and accurate analysis of molnupiravir, emphasizing its role in supporting fast-paced pharmaceutical research and development (Reçber et al., 2022).
- Sensitive Analysis of Idarubicin in Human Urine and Plasma by Liquid Chromatography with Fluorescence Detection: This application underlines the Discovery® HS C18 column′s high sensitivity and robustness in clinical diagnostics, crucial for monitoring therapeutic drugs and their metabolites in complex biological matrices (Maliszewska et al., 2020).
Características e benefícios
- Estável, com pouco vazamento, para aplicações de LC-MS
- Escalável do analítico ao preparatório
- Altamente estável para garantir excelente reprodutibilidade entre corridas e entre lotes
- Maior hidrofobicidade para melhor resolução de analitos difíceis
Informações legais
Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
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Conteúdo relacionado
HPLC DiscoveryBIO HS C18 products. Available in 3µm, 5µm and 10µm particle sizes.
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