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V0513

Sigma-Aldrich

L-Valine

98.5-101.0%, suitable for cell culture, non-animal source, meets EP, JP, USP testing specifications

Sinônimo(s):

(S)-α-Aminoisovaleric acid, L-2-Amino-3-methylbutanoic acid

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About This Item

Fórmula linear:
(CH3)2CHCH(NH2)CO2H
Número CAS:
72-18-4
Peso molecular:
117.15
Beilstein:
1721136
Número CE:
200-773-6
Número MDL:
MFCD00064220
Código UNSPSC:
12352209
eCl@ss:
32160406
ID de substância PubChem:
24900696
NACRES:
NA.26

product name

L-Valine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%

fonte biológica

non-animal source

Nível de qualidade

300

Agency

USP/NF
meets EP testing specifications
meets JP testing specifications
meets USP testing specifications

Ensaio

98.5-101.0%

forma

powder

qualidade

meets EP, JP, USP testing specifications

técnica(s)

cell culture | mammalian: suitable

Impurezas

endotoxin, tested

cor

white

pf

295-300 °C (subl.) (lit.)

solubilidade

H2O: 25 mg/mL

aplicação(ões)

pharmaceutical (small molecule)

cadeia de caracteres SMILES

CC(C)[C@H](N)C(O)=O

InChI

1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m0/s1

chave InChI

KZSNJWFQEVHDMF-BYPYZUCNSA-N

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Categorias relacionadas

Aplicação

L-Valine as been used in the preparation of amino acid supplemented media to culture primary hepatocytes.

Ações bioquímicas/fisiológicas

Valine is an essential amino acid, involved in the biosynthesis of glutamine and alanine. Valine being a branched-chain amino acid (BCAA) maintains a balance among the BCAAs. L-Valine serves as an energy fuel. Long term deficiency of L-Valine leads to growth failure, organ damage and loss of muscle mass.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Martin Kohlmeier
Nutrient Metabolism: Structures, Functions, and Genes, 390-390 (2015)
Recapitulation of metabolic defects in a model of propionic acidemia using patient-derived primary hepatocytes.
Chapman KA
Molecular Genetics and Metabolism, 117(3), 355-362 (2016)
Sonia Jego et al.
Nature neuroscience, 16(11), 1637-1643 (2013-09-24)
Rapid-eye movement (REM) sleep correlates with neuronal activity in the brainstem, basal forebrain and lateral hypothalamus. Lateral hypothalamus melanin-concentrating hormone (MCH)-expressing neurons are active during sleep, but their effects on REM sleep remain unclear. Using optogenetic tools in newly generated
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Nature neuroscience, 16(11), 1671-1677 (2013-10-08)
Neocortical activity can evoke sensory percepts, but the cellular mechanisms remain poorly understood. We trained mice to detect single brief whisker stimuli and report perceived stimuli by licking to obtain a reward. Pharmacological inactivation and optogenetic stimulation demonstrated a causal
Ying-Lin Chen et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(21), 9013-9020 (2013-05-24)
The translation of dendritic microtubule-associated protein 1B (MAP1B) is exaggerated upon group I mGluR activation leading to AMPA receptor (AMPAR) endocytosis and consequent long-term depression. However, the mechanisms of regulation of MAP1B protein synthesis in the mature dendrites remain unclear.
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