T7329

Taurolidine

>97% (NMR), powder

• Sinônimo(s): 4,4′-Methylenebis(tetrahydro-1,2,4-sulfadiazine 1,1-dioxide), Taurolin, Tauroline
• Fórmula empírica (Notação de Hill): C₇H₁₆N₄O₄S₂
• Número CAS: 19388-87-5
• Peso molecular: 284.36
• Número CE: 243-016-5
• Número MDL: MFCD00865076
• Código UNSPSC: 12352200
• ID de substância PubChem: 329826864
• NACRES: NA.77

Propriedades

• Nível de qualidade: 100
• Ensaio: >97% (NMR)
• Formulário: powder
• condição de armazenamento: protect from light
• cor: white to off-white
• solubilidade: DMSO: >20 mg/mL
• temperatura de armazenamento: room temp
• cadeia de caracteres SMILES: O=S1(=O)CCN(CN1)CN2CCS(=O)(=O)NC2
• InChI: 1S/C7H16N4O4S2/c12-16(13)3-1-10(5-8-16)7-11-2-4-17(14,15)9-6-11/h8-9H,1-7H2
• chave InChI: AJKIRUJIDFJUKJ-UHFFFAOYSA-N

Descrição

Ações bioquímicas/fisiológicas

Taurolidine is a broad spectrum antibiotic with antineoplastic activity, which induces apoptosis and decreases tumor cell proliferation. Taurolidine has been used with TNF-related-apoptosis-inducing ligand (TRAIL) to characterize synergistic responses in many apoptosis related signaling-proteins. Tauroline is also being used as a tool to study the various mechanisms of apoptosis and necrosis.

Taurolidine is a broad spectrum antibiotic with antineoplastic activity; induces apoptosis and decreases tumor cell proliferation.

Taurolidine is an antibacterial agent that can be used for the treatment of peritonis. It has also been used as an antiendoxic substance for systematic inflammatory response syndrome and as an anti-angiogenic agent for tumors. Furthermore, studies have reported that taurolidine can be used for the prevention of multiple catheter-related bloodstream infections.

Nota de preparo

Taurolidine is soluble in DMSO at a concentration that is greater than 20 mg/ml.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable