SRP8030

Fn14 (human): FC (human)

recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)

• Sinônimo(s): CD266, E1A-associated protein p300, FGF-inducible 14, Tumor necrosis factor receptor superfamily member 12A
• Código UNSPSC: 51111800
• NACRES: NA.32

Propriedades

• fonte biológica: human
• recombinante: expressed in HEK 293 cells
• Ensaio: >95% (SDS-PAGE)
• Formulário: lyophilized
• peso molecular: ~35 kDa by SDS-PAGE
• embalagem: pkg of 50 μg
• condição de armazenamento: avoid repeated freeze/thaw cycles
• Impurezas: <0.1 EU/μg endotoxin, tested
• cor: white
• nº de adesão UniProt: Q9NP84
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• Informações sobre genes: human ... TNFRSF12A(51330)

Descrição

Descrição geral

TWEAK is a cytokine that controls proliferation, migration, differentiation, apoptosis, angiogenesis and inflammation. TWEAK binds to Fn14, a highly inducible cell-surface receptor that is linked to several intracellular signalling pathways, including the nuclear factor-B (NF-kappaB) pathway. The TWEAK-Fn14 axis plays a beneficial role in tissue repair following acute injury and may contribute to cancer, chronic autoimmune diseases and acute ischaemic stroke.

forma física

Lyophilized from PBS.

Reconstituição

Reconstitute with 50 μL deionized water.

Outras notas

The extracellular region of human FN14 (aa 28-75) is fused at the C-terminus to the Fc portion of human IgG1.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable