SML3091

Irresistin-16

≥98% (HPLC)

• Sinônimo(s): 7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine,7-([1,1?-biphenyl]-4-ylmethyl), IRS-16
• Fórmula empírica (Notação de Hill): C₂₃H₁₉N₅
• Número CAS: 2624247-60-3
• Peso molecular: 365.43
• Código UNSPSC: 51111800
• NACRES: NA.77

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥98% (HPLC)
• Formulário: powder
• cor: white to beige
• solubilidade: DMSO: 2 mg/mL, clear
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: NC1=NC(N)=NC2=C1C3=C(C=C2)N(CC4=CC=C(C=C4)C5=CC=CC=C5)C=C3
• InChI: 1S/C23H19N5/c24-22-21-18-12-13-28(20(18)11-10-19(21)26-23(25)27-22)14-15-6-8-17(9-7-15)16-4-2-1-3-5-16/h1-13H,14H2,(H4,24,25,26,27)

Descrição

Ações bioquímicas/fisiológicas

Irresistin-16, an SCH 79797 derivative, is a broad spectrum bactericidal antibiotic that is effective in both gram-positive and gram-negative bacteria and exhibits low frequency of resistance. Irresistin-16 act through interruption of bacterial folate metabolism and bacterial membrane integrity. It inhibits E. coli dihydrofolate reductase FolA. Irresistin-16 is effective in mouse gonorrhea infection model.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable