SML1572

Gentiopicroside

≥98% (HPLC)

• Sinônimo(s): (3S,4R)-4-ethenyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,6-dihydro-3H-pyrano[3,4-c]pyran-8-one, (5R,6S)-5-Ethenyl-6-(-D-glucopyranosyloxy)-5,6-dihydro-1H,3H-Pyrano[3,4-c]pyran-1-one, (5R-trans)-5-ethenyl-6-(-D-glucopyranosyloxy)-5,6-dihydro-1H,3H-pyrano[3,4-c]pyran-1-one, Gentiopicrin, NSC606402
• Fórmula empírica (Notação de Hill): C₁₆H₂₀O₉
• Número CAS: 20831-76-9
• Peso molecular: 356.32
• Número CE: 244-070-2
• Número MDL: MFCD00075700
• Código UNSPSC: 12352200
• ID de substância PubChem: 329825970
• NACRES: NA.77

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥98% (HPLC)
• Formulário: powder
• atividade óptica: [α]/D -185 to -205°, c = 1 in H₂O
• cor: white to beige
• solubilidade: H₂O: 20 mg/mL, clear
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: C=C[C@H]1[C@H](O[C@]2([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)OC=C3C(OCC=C31)=O
• InChI: 1S/C16H20O9/c1-2-7-8-3-4-22-14(21)9(8)6-23-15(7)25-16-13(20)12(19)11(18)10(5-17)24-16/h2-3,6-7,10-13,15-20H,1,4-5H2/t7-,10-,11-,12+,13-,15+,16+/m1/s1
• chave InChI: DUAGQYUORDTXOR-GPQRQXLASA-N

Descrição

Descrição geral

Gentiopicroside is a natural Iridoid compound, found in Chinese medicinal herbs Gentiana scabra Bge. and Gentiana macrophylla Pall.

Ações bioquímicas/fisiológicas

Gentiopicroside is an important active component of secoiridoid glycosides from Gentiana macrophylla Pall that exhibit anti-inflammatory, antibacterial and liver protecting activities. Gentiopicroside protects chondrocytes from IL-1β-induced inflammation response.

Gentiopicroside possesses analgesic, anti proliferative, wound healing and antioxidant properties (free radical scavenging activity). Gentiopicroside shows low oral bioavailability, hence it establishes its therapeutic action after metabolism.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable