SML0309

Sodium phenylbutyrate

≥98% (HPLC)

• Sinônimo(s): 4-PBA, 4-Phenylbutyric acid, 4-phenylbutyrate, Buphenyl, Sodium 4-phenylbutyrate, TriButyrate
• Fórmula empírica (Notação de Hill): C₁₀H₁₁NaO₂
• Número CAS: 1716-12-7
• Peso molecular: 186.18
• Número MDL: MFCD00800247
• Código UNSPSC: 12352200
• ID de substância PubChem: 329825314
• NACRES: NA.77

Propriedades

• Ensaio: ≥98% (HPLC)
• Formulário: powder
• cor: white to beige
• solubilidade: H₂O: ≥5 mg/mL
• temperatura de armazenamento: room temp
• cadeia de caracteres SMILES: [Na+].[O-]C(=O)CCCc1ccccc1
• InChI: 1S/C10H12O2.Na/c11-10(12)8-4-7-9-5-2-1-3-6-9;/h1-3,5-6H,4,7-8H2,(H,11,12);/q;+1/p-1
• chave InChI: VPZRWNZGLKXFOE-UHFFFAOYSA-M

Descrição

Descrição geral

Sodium phenylbutyrate stimulates urinary nitrogen excretion. It is a prodrug, which undergoes β-oxidation to phenylacetate. Sodium phenylbutyrate is used to treat urea cycle disorder. It might be associated with menstrual dysfunction, amenorrhea and painful mucositis of the esophagus and stomach.

Aplicação

Sodium phenylbutyrate has been used as an endoplasmic reticulum (ER) stress inhibitor to study the role of ER stress in the expression of betatrophin.

Ações bioquímicas/fisiológicas

Sodium phenylbutyrate is a histone deacetylase inhibitor.

Características e benefícios

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable