SMB01045

Isoliquiritin

≥90% (LC/MS-ELSD)

• Sinônimo(s): 4-beta-D-glucopyranosyloxy-2′,4′-dihydroxy-trans-chalcone, Isoliquiritoside
• Fórmula empírica (Notação de Hill): C₂₁H₂₂O₉
• Número CAS: 5041-81-6
• Peso molecular: 418.39
• Número MDL: MFCD00272145
• Código UNSPSC: 12352205
• NACRES: NA.25

Propriedades

• fonte biológica: plant
• Ensaio: ≥90% (LC/MS-ELSD)
• Formulário: solid
• peso molecular: 418.39
• aplicação(ões): metabolomics; vitamins, nutraceuticals, and natural products
• temperatura de armazenamento: −20°C
• InChI: 1S/C21H22O9/c22-10-17-18(26)19(27)20(28)21(30-17)29-13-5-1-11(2-6-13)3-8-15(24)14-7-4-12(23)9-16(14)25/h1-9,17-23,25-28H,10H2/b8-3+/t17-,18-,19+,20-,21-/m1/s1
• chave InChI: YNWXJFQOCHMPCK-LXGDFETPSA-N

Descrição

Descrição geral

Isoliquiritin, also known as Isoliquiritoside, is a flavonoid belongs to the class of dihydrochalcones commonly available from Glycyrrhiza Sp. plants. This plant metabolite exhibits various biological activities, including antioxidant, antifungal, anti-HIV, anticancer properties.

Aplicação

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Ações bioquímicas/fisiológicas

Isoliquiritin triggers apoptotic cell death by increasing the levels of p53 and p21 in A549 non-small cell lung cancer cells while also inhibiting the p53-dependent pathway and revealing interactions with Akt activities. Futher, Isoliquiritin has demonstrated neuroprotective activity against oxidative stress and has the capability to restrain the growth of microbial pathogens.

Características e benefícios

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Outras notas

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Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable