SMB00576

Dioscin

≥95% (HPLC)

• Sinônimo(s): Collettiside III, Diosgenin bis-α-L-rhamnopyranosyl-(1→2,1→4)-beta-D-glucopyranoside, Polyphyllin III
• Fórmula empírica (Notação de Hill): C₄₅H₇₂O₁₆
• Número CAS: 19057-60-4
• Peso molecular: 869.04
• Número MDL: MFCD02094174
• Código UNSPSC: 12352205
• ID de substância PubChem: 329825065
• NACRES: NA.25

Propriedades

• Nível de qualidade: 200
• Ensaio: ≥95% (HPLC)
• forma: powder
• aplicação(ões): metabolomics; vitamins, nutraceuticals, and natural products
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: C[C@@]12[C@]([C@@H]3C)([H])[C@](O[C@]34CC[C@@H](C)CO4)([H])C[C@@]1([H])[C@@](CC=C5[C@@]6(CC[C@H](O[C@@](O[C@H](CO)[C@@H](O[C@@](O[C@@H](C)[C@H](O)[C@H]7O)([H])[C@@H]7O)[C@@H]8O)([H])[C@@H]8O[C@@](O[C@@H](C)[C@H](O)[C@H]9O)([H])[C@@H]9O)C5)C)([H])[C@]6([H]
• InChI: 1S/C45H72O16/c1-19-9-14-45(54-18-19)20(2)30-28(61-45)16-27-25-8-7-23-15-24(10-12-43(23,5)26(25)11-13-44(27,30)6)57-42-39(60-41-36(52)34(50)32(48)22(4)56-41)37(53)38(29(17-46)58-42)59-40-35(51)33(49)31(47)21(3)55-40/h7,19-22,24-42,46-53H,8-18H2,1-6H3/t19-,20+,21+,22+,24+,25-,26+,27+,28+,29-,30+,31+,32+,33-,34-,35-,36-,37+,38-,39-,40+,41+,42-,43+,44+,45-/m1/s1
• chave InChI: VNONINPVFQTJOC-ZGXDEBHDSA-N

Descrição

Descrição geral

Dioscin is a highly fat-soluble steroid saponin found in many varieties of Dioscoreaceae plants including Dioscorea nipponica Makino.

Aplicação

Dioscin has been used to study its anti-inflammatory and protective effects on neuron damage due to ischemia‑reperfusion injury (IRI). It has also been used as a commercial saponin to perform a comparative analysis and study its permeabilization power in respirometry technique.

Ações bioquímicas/fisiológicas

Dioscin is a potent anti-tumor agent and elicits strong anti-cancer properties against several cancers like breast, renal, lung, and liver cancers, gastric carcinoma, acute myeloid leukemia. It displays hepatoprotective, cardioprotective, and nephroprotective properties. Dioscin also exerts anti-diabetic, antifungal, and antiviral effects.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable