SAB5700562

Anti-Phospho-GRIN2B-Y1070 antibody produced in rabbit

• Sinônimo(s): EIEE27, GRIN2B, GluN2B, MRD6, NMDAR2B, NR2B, hNR3
• Código UNSPSC: 12352203
• NACRES: NA.43
• clone: polyclonal
• application: WB
• reatividade de espécies: rat, human, mouse
• técnica(s): western blot: 1:500-1:2000

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: 166
• reatividade de espécies: rat, human, mouse
• concentração: 0.94mg/ml
• técnica(s): western blot: 1:500-1:2000
• nº de adesão UniProt: Q13224
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pTyr1070)
• Informações sobre genes: human ... GRIN2B(2904)

Descrição

Descrição geral

This gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate. The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation. Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia.

Imunogênio

A phospho synthetic peptide corresponding to residues surrounding Y1070 of human GRIN2B.

forma física

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Armazenamento e estabilidade

Store at -20℃. Avoid freeze / thaw cycles.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable