SAB5700295

Anti-Phospho-EIF4EBP1-T70 antibody produced in rabbit

• Sinônimo(s): 4E-BP1, 4EBP1, BP-1, EIF4EBP1, PHAS-I
• Código UNSPSC: 12352203
• NACRES: NA.43

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• peso molecular: 12
• reatividade de espécies: mouse, human
• concentração: 1.78 mg/ml
• técnica(s): western blot: 1:500-1:2000
• nº de adesão UniProt: Q13541
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pThr70)
• Informações sobre genes: human ... EIF4EBP1(1978)

Descrição

Descrição geral

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Imunogênio

A synthetic phosphorylated peptide around T70 of human EIF4EBP1 (NP_004086.1).

forma física

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Armazenamento e estabilidade

Store at -20℃. Avoid freeze / thaw cycles.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable