SAB5500057

Anti-CD3 antibody, Rabbit monoclonal

recombinant, expressed in proprietary host, clone SP162, affinity isolated antibody

• Sinônimo(s): Anti-CD3epsilon, Anti-IMD18, Anti-T3E, Anti-TCRE
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• recombinante: expressed in proprietary host
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: SP162, monoclonal
• reatividade de espécies: human (tested)
• reatividade da espécie (prevista por homologia): rat, chicken, rabbit, mouse, pig, bovine, dog
• técnica(s): flow cytometry: 1:150; immunoblotting: 1:150; immunohistochemistry: 1:150
• Isotipo: IgG
• nº de adesão UniProt: P07766
• Condições de expedição: wet ice
• temperatura de armazenamento: 2-8°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... CD3E(916)

Descrição

Descrição geral

CD3E (CD3e molecule) gene is mapped to human chromosome 11q23.3. This gene encodes fora subunit of T-cell regulator (TCR) protein complex. It possesses IgG (immunoglobulin G)-like extracelluar domain at the N-terminal, a transmembrane domain, a peptide bridge and an immunoreceptor tyrosine-based activation motif (ITAM) towards the cytoplasm. The protein also contains basic residue-rich sequence (BRS).

This antibody reacts with the intracytoplasmic portion of the CD3 antigen expressed by T cells. It stains human T cells in both the cortex and medulla of the thymus and in peripheral lymphoid tissues. This antibody is suitable for staining normal and neoplastic T cells in formalin-fixed, paraffin-embedded tissues.

Imunogênio

Synthetic peptide corresponding to internal region of the epsilon chain of human CD3 protein.

Aplicação

Anti-CD3 antibody, Rabbit monoclonal has been used in immunohistochemistry.

Ações bioquímicas/fisiológicas

CD3E (CD3e molecule) gene is associated with actin cytoskeletal rearrangement, through activation of a number of signaling pathways. CD3E is essential for membrane binding of T-cell regulator (TCR) protein complex.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable