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Key Documents

SAB5200106

Sigma-Aldrich

Anti-SCNN1B antibody produced in rabbit

1 mg/mL, affinity isolated antibody

Sinônimo(s):

Anti-ENaC Beta, Anti-Scnn1b

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

100

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

forma

buffered aqueous glycerol solution

peso molecular

antigen predicted mol wt 87 kDa

reatividade de espécies

mouse, human, rat

concentração

1 mg/mL

técnica(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

nº de adesão NCBI

NP_036780

nº de adesão UniProt

P51168

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

rat ... Scnn1b(24767)

Descrição geral

Sodium channel epithelial 1 β subunit (SCNN1B) is expressed in the posterior cerebral artery of rats. It is one of the subunits of epithelial sodium channels. The gene ID of the protein is 24767.

Especificidade

Detects ~87 kDa.

Imunogênio

AA617–638 of the rat sequence

Ações bioquímicas/fisiológicas

Sodium channel epithelial 1 β subunit (SCNN1B) is involved in sodium transport in the epithelium.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

PBS, 50% glycerol, and 0.09% sodium azide

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

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Chengbiao Zhang et al.
American journal of physiology. Renal physiology, 312(4), F682-F688 (2017-04-04)
Mice transgenic for genomic segments harboring PHAII (pseudohypoaldosteronism type II) mutant Wnk4 (with-No-Lysine kinase 4) (TgWnk4PHAII) have hyperkalemia which is currently believed to be the result of high activity of Na-Cl cotransporter (NCC). This leads to decreasing Na+ delivery to
Lijun Wang et al.
Journal of the American Society of Nephrology : JASN, 26(11), 2678-2690 (2015-04-08)
Kcnj10 encodes the inwardly rectifying K(+) channel Kir4.1 in the basolateral membrane of the distal convoluted tubule (DCT) and is activated by c-Src. However, the regulation and function of this K(+) channel are incompletely characterized. Here, patch-clamp experiments in Kcnj10-transfected
Eok-Cheon Kim et al.
Experimental physiology, 97(4), 544-555 (2011-11-18)
It has been suggested that mechanosensitive ion channels initiate myogenic responses in vessels; however, the molecular identity of the mechanosensitive ion channel complex is unknown. Although previous reports have suggested that epithelial Na(+) channel (ENaC) proteins are mechanotransducers in arteries
Md Shahrier Amin et al.
Hypertension (Dallas, Tex. : 1979), 54(4), 860-867 (2009-07-29)
To elucidate the role of epithelial sodium channels (ENaCs) and Na(+)-K(+)-ATPase in Na(+) transport by the choroid plexus, we studied ENaC expression and Na(+) transport in the choroid plexus. Lateral ventricle choroid plexuses were obtained from young male Wistar, Dahl

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