SAB4700353
Monoclonal Anti-IgE-FITC antibody produced in mouse
clone BE5, purified immunoglobulin, buffered aqueous solution
Sinônimo(s):
Anti-IGHE
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About This Item
Código UNSPSC:
12352203
NACRES:
NA.41
Produtos recomendados
fonte biológica
mouse
Nível de qualidade
conjugado
FITC conjugate
forma do anticorpo
purified immunoglobulin
tipo de produto de anticorpo
primary antibodies
clone
BE5, monoclonal
Formulário
buffered aqueous solution
reatividade de espécies
human
concentração
0.1 mg/mL
técnica(s)
flow cytometry: suitable
Isotipo
IgG1
nº de adesão NCBI
nº de adesão UniProt
Condições de expedição
wet ice
temperatura de armazenamento
2-8°C
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... IGHE(3497)
Descrição geral
Immunoglobulin E (IgE) is encoded by the gene mapped to human chromosome 14q32.33. IgE belongs to the immunoglobulin family and consists of epsilon(ε) heavy chain in the constant (C) region. IgE has a monomeric structure with an extra domain in the constant region.
The antibody BE5 reacts with human IgE; it recognizes an epitope different from the ones recognized by 4G7 and 4H10 antibodies to IgE.
Imunogênio
Purified human IgE
Aplicação
The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 5 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
Ações bioquímicas/fisiológicas
Immunoglobulin E (IgE) binds very tightly to Fc receptors on basophils and mast cells. Thus, it plays a major role in stimulating allergic reactions. Elevated expression of the gene has been associated with the development of hyper IgE Syndrome (HIES), hay fever, atopic skin diseases such as eczema, anaphylactic shock and IgE-myeloma. In addition, overexpression of IgE is also observed in allergy/asthma. Therefore, increased levels of serum IgE can be considered as a diagnosis for asthma. IgE expression is down-regulated in congenital agammaglobulinemia and hypogammaglobulinemia because of faulty metabolism or synthesis of immunoglobulins.
Características e benefícios
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
forma física
Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Escolha uma das versões mais recentes:
Já possui este produto?
Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.
Hans D. Ochs, C. I. Edward Smith, Jennifer M.
Primary Immunodeficiency Diseases: A Molecular and Cellular Approach (2006)
Binie Ver Lipps
Immunoglobulin E (Ige): Novel Treatment for Lowering the Concentration of Ige (2009)
N. Franklin Adkinson, Jr., Bruce S. Bochner, Wesley Burks, William W. Busse, Stephen T. Holgate
Middleton's Allergy: Principles and Practice
(2013)
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