QBD10247
Thiol-dPEG®4-acid
>95% (HPLC)
Sinônimo(s):
Carboxy-PEG4-thiol, HS-PEG4-COOH, Thiol-PEG-acid, Thiol-PEG4-COOH, Thiol-PEG4-acid
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About This Item
Fórmula empírica (Notação de Hill):
C11H22O6S
Peso molecular:
282.35
Número MDL:
Código UNSPSC:
12352106
NACRES:
NA.22
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Ensaio
>95% (HPLC)
forma
solid or viscous liquid
adequação da reação
reaction type: Pegylations
arquitetura do polímero
shape: linear
functionality: heterobifunctional
Condições de expedição
ambient
temperatura de armazenamento
−20°C
Características e benefícios
Thiol-dPEG4-acid is a sulfhydryl-containing, crosslinking PEGylation reagent that has a cross-bridge of monodisperse polyethylene glycol. The single molecular weight, discrete-length PEG (dPEG) chain is 16 atoms (18.3 Å) long. The sulfhydryl end of the crosslinker reacts with gold (forming dative bonds) and with thiol-reactive functional groups such as maleimide, bromoacetyl, SPDP, and thiol. The carboxylic acid end of the molecule couples to free amines using EDC or any suitable carbodiimide. An acylating agent such as N-hydroxysuccinimide (NHS) or 2,3,5,6-tetrafluorophenol (TFP) can enhance coupling efficiency. The carboxylate must react after the sulfhydryl conjugation.
Informações legais
Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
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