SAB4700059

Monoclonal Anti-CD4 , (N-terminal) antibody produced in mouse

clone MEM-241, purified immunoglobulin, buffered aqueous solution

• Sinônimo(s): Anti-CD4mut, Anti-IMD79, Anti-OKT4D
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: MEM-241, monoclonal
• Formulário: buffered aqueous solution
• reatividade de espécies: human
• concentração: 1 mg/mL
• técnica(s): flow cytometry: suitable
• Isotipo: IgG1
• nº de adesão NCBI: NM_000616.4
• nº de adesão UniProt: P01730
• Condições de expedição: wet ice
• temperatura de armazenamento: 2-8°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... CD4(920)

Descrição

Descrição geral

CD4 (cluster of differentiation 4) molecule is encoded by the gene mapped to human chromosome 12p13.31. The encoded protein is mainly localized on the surface of specific leukocytes. CD4 is characterized with a four ecto-domains (D1-D4) of which D1, D2 and D4 contain disulfide bonds.

Imunogênio

2 N-terminal domains of human CD4 fused to human IgG1 Fc

Aplicação

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 1 μg/mL of sample of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Ações bioquímicas/fisiológicas

CD4 (cluster of differentiation 4) facilitates the activation of immunostimulatory T-cells. It serves as a primary receptor for HIV-1 entry. The encoded protein also plays a key role in altering cell elasticity. Elevated expression of soluble CD4 has been observed in patients of infectious and chronic inflammatory diseases and rheumatoid arthritis (RA). Thus, this protein can be used as a potential diagnostic marker for the development of RA.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable