SAB4504315

Anti-phospho-PI3-kinase p85-α (pTyr⁶⁰⁷) antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): Anti-AGM7, Anti-GRB1, Anti-IMD36, Anti-p85, Anti-p85-ALPHA
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 83 kDa
• reatividade de espécies: human, mouse, rat
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:1000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• nº de adesão NCBI: P27986
• nº de adesão UniProt: P27986
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pTyr607)
• Informações sobre genes: human ... PIK3R1(5295)

Descrição

Descrição geral

PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1) is a pleiotropic gene, that codes for a p85α regulatory subunit of phosphatidylinositol-3 kinase (PI3K). This gene is mapped to human chromosome 5q13.

Imunogênio

The antiserum was produced against synthesized peptide derived from human PI3-kinase p85-alpha around the phosphorylation site of Tyr607.

Immunogen Range: 573-622

Ações bioquímicas/fisiológicas

PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1) is known to mediate immune cell differentiation, development and function. Mutations in PIK3R1 gene result in SHORT syndrome, hyper IgM syndrome, lymphadenopathy and short stature.

Características e benefícios

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forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable