SAB4301399

Anti-phospho-DRP1 (pSer⁶³⁷) antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): DLP1, DNM1L, DRP1, DVLP, Dymple
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• peso molecular: 82 kDa
• reatividade de espécies: human
• concentração: 1.0 mg/mL
• técnica(s): western blot: 1:500-1:1000 (Cell Lysate)
• Isotipo: IgG
• nº de adesão: NP_036192.2.
• nº de adesão UniProt: O00429
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pSer637)
• Informações sobre genes: human ... DNM1L(10059)

Descrição

Descrição geral

Dynamin related protein 1 (DRP1) is a dynamin-related guanosine triphosphatase. The gene is located on human chromosome 12p11.21. DRP1 is a cytosolic protein, which is also present on the outer mitochondrial membrane.

Especificidade

The antibody detects endogenous levels of DRP1 only when phosphorylated at serine 637.

Imunogênio

Peptide sequence around phosphorylation site of Serine637(K-L-S(p)-A-R) derived from Human DRP1.

Aplicação

Anti-phospho-DRP1 (pSer⁶³⁷) antibody produced in rabbit has been used in immunoblotting and western blotting.

Ações bioquímicas/fisiológicas

Dynamin related protein 1 (DRP1) is an important regulator of mitochondrial fission and peroxisomal division. It regulates proper mitochondrial function, apoptosis and necrosis. Mutations in this gene is associated with Alzheimer′s disease.

Características e benefícios

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forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable