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SAB4300614

Sigma-Aldrich

Anti-ARNTL antibody produced in rabbit

affinity isolated antibody

Sinônimo(s):

Anti-BMAL1 antibody produced in rabbit, Anti-BMAL1c antibody produced in rabbit, Anti-JAP3 antibody produced in rabbit, Anti-MGC47515 antibody produced in rabbit, Anti-aryl hydrocarbon receptor nuclear translocator-like antibody produced in rabbit

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About This Item

Número MDL:
Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

rabbit

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

forma

buffered aqueous solution

peso molecular

~69 kDa

reatividade de espécies

rat, mouse, human

concentração

1 mg/mL

técnica(s)

western blot: 1:500-1:1000

Isotipo

IgG

sequência de imunogênio

(S-S-S-I-L)

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... ARNTL(406)

Imunogênio

Peptide sequence around aa. 569-573 (S-S-S-I-L), according to the protein ARNTL.

Aplicação

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Descrição-alvo

ARNTL-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins.

forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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Brian A Hodge et al.
Skeletal muscle, 5, 17-17 (2015-05-23)
Skeletal muscle is a major contributor to whole-body metabolism as it serves as a depot for both glucose and amino acids, and is a highly metabolically active tissue. Within skeletal muscle exists an intrinsic molecular clock mechanism that regulates the
Brian A Hodge et al.
eLife, 8 (2019-02-23)
In the present study we show that the master myogenic regulatory factor, MYOD1, is a positive modulator of molecular clock amplitude and functions with the core clock factors for expression of clock-controlled genes in skeletal muscle. We demonstrate that MYOD1
Michael L Rossetti et al.
American journal of physiology. Endocrinology and metabolism, 317(4), E631-E645 (2019-07-31)
Androgen depletion in humans leads to significant atrophy of the limb muscles. However, the pathways by which androgens regulate limb muscle mass are unclear. Our laboratory previously showed that mitochondrial degradation was related to the induction of autophagy and the

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