SAB3501078
Anti-TMIGD1 antibody produced in rabbit
affinity isolated antibody
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About This Item
Código UNSPSC:
12352203
NACRES:
NA.41
conjugado:
unconjugated
application:
ELISA
clone:
polyclonal
reatividade de espécies:
rat, mouse, human
citations:
1
técnica(s):
ELISA: suitable
immunoblotting: suitable
immunoblotting: suitable
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fonte biológica
rabbit
Nível de qualidade
conjugado
unconjugated
forma do anticorpo
affinity isolated antibody
tipo de produto de anticorpo
primary antibodies
clone
polyclonal
Formulário
buffered aqueous solution
peso molecular
predicted mol wt 29 kDa
reatividade de espécies
rat, mouse, human
concentração
1 mg/mL
técnica(s)
ELISA: suitable
immunoblotting: suitable
nº de adesão NCBI
nº de adesão UniProt
Condições de expedição
wet ice
temperatura de armazenamento
−20°C
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... TMIGD1(388364)
Descrição geral
TMIGD1 (Transmembrane and immunoglobulin domain containing 1) is a novel adhesion molecule expressed in several organs and tissues, specifically in renal tubular epithelial cells. It is composed of two putative immunoglobulin domains, which mediates self-dimerization.
Imunogênio
Antibody was raised against an 18 amino acid peptide near the center of human TMIGD1.
Aplicação
Anti-TMIGD1 antibody produced in rabbit is suitable for immunoblot and ELISA.
Ações bioquímicas/fisiológicas
TMIGD1 (Transmembrane and immunoglobulin domain containing 1) is involved in various cellular processes such as regulation of cell structure, cell-cell adhesion, and cellular movement. Its extracellular domain stabilizes the cell morphology and cell-cell interaction. TMIGD1 plays an important role in cell survival by protecting it from oxidative cell injury. It protects cells from oxidative and nutrient-deprivation-induced cell injury by stabilizing the transepithelial electric resistance and permeability of renal epithelial cells.
Características e benefícios
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Ligação
The action of this antibody can be blocked using blocking peptide SBP3501078.
forma física
Supplied at 1 mg/mL in PBS with 0.02% sodim azide.
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
10 - Combustible liquids
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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Koji Fujimoto et al.
Gastroenterology, 123(6), 1941-1948 (2002-11-28)
The surface epithelium of the colon is being replaced constantly with cells derived from the stem cells of the crypt. Although the location of the stem cells is known, there are no markers for these cells. This study tested the
Junli Yan et al.
Proceedings of the National Academy of Sciences of the United States of America, 104(6), 1841-1846 (2007-02-01)
Tight regulation of p53 is essential for maintaining normal cell growth. Here we report that BLIMP1 acts in an autoregulatory feedback loop that controls p53 activity through repression of p53 transcription. p53 binds to and positively regulates BLIMP1, which encodes
Elisa Cattaneo et al.
EMBO molecular medicine, 3(6), 334-347 (2011-05-04)
Improved colonoscopy is revealing precancerous lesions that were frequently missed in the past, and ∼30% of those detected today have nonpolypoid morphologies ranging from slightly raised to depressed. To characterize these lesions molecularly, we assessed transcription of 23,768 genes in
Emad Arafa et al.
The American journal of pathology, 185(10), 2757-2767 (2015-09-08)
Oxidative damage to renal tubular epithelial cells is a fundamental pathogenic mechanism implicated in both acute kidney injury and chronic kidney diseases. Because epithelial cell survival influences the outcome of acute kidney injury and chronic kidney diseases, identifying its molecular
Hilary F Clark et al.
Genome research, 13(10), 2265-2270 (2003-09-17)
A large-scale effort, termed the Secreted Protein Discovery Initiative (SPDI), was undertaken to identify novel secreted and transmembrane proteins. In the first of several approaches, a biological signal sequence trap in yeast cells was utilized to identify cDNA clones encoding
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