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SAB3500901

Sigma-Aldrich

Anti-ANTHRAX PROTECTIVE ANTIGEN antibody produced in rabbit

affinity isolated antibody

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

rabbit

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

forma

buffered aqueous solution

reatividade de espécies

bacteria

concentração

1 mg/mL

técnica(s)

ELISA: suitable

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

Descrição geral

Anthrax toxin comprises of protective antigen (PA), lethal factor (LF) and edema factor (EF).

Imunogênio

Antibody was raised against a synthetic peptide corresponding to 14 amino acids at the carboxy terminus of the Anthrax protective antigen protein.

Ações bioquímicas/fisiológicas

B. anthracis liberates toxins that plays a vital role in establishing and maintaining infection.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Ligação

The action of this antibody can be blocked using blocking peptide SBP3500901.

forma física

Supplied at 1 mg/mL in PBS with 0.02% sodim azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

10 - Combustible liquids

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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Detection of anthrax protective antigen (PA) using europium labeled anti-PA monoclonal antibody and time-resolved fluorescence.
Stoddard RA, et al.
Journal of Immunological Methods, 408, 78-88 (2014)
Mahtab Moayeri et al.
Current opinion in microbiology, 7(1), 19-24 (2004-03-24)
Anthrax lethal toxin is a multi-functional virulence factor that has evolved to target multiple host functions to allow for optimal establishment of Bacillus anthracis infection. The toxin appears to play a role in all stages of infection, from germination to
Recognition and management of anthrax--an update.
M N Swartz
The New England journal of medicine, 345(22), 1621-1626 (2001-11-13)
K A Bradley et al.
Nature, 414(6860), 225-229 (2001-11-09)
The tripartite toxin secreted by Bacillus anthracis, the causative agent of anthrax, helps the bacterium evade the immune system and can kill the host during a systemic infection. Two components of the toxin enzymatically modify substrates within the cytosol of
Heather M Scobie et al.
Proceedings of the National Academy of Sciences of the United States of America, 100(9), 5170-5174 (2003-04-18)
Bacillus anthracis secretes two bipartite toxins thought to be involved in anthrax pathogenesis and resulting death of the host. The current model for intoxication is that protective antigen (PA) toxin subunits bind a single group of cell-surface anthrax toxin receptors

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