SAB3500242

Anti-DARC antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Sinônimo(s): Anti-CADM3, Anti-Cell adhesion molecule 3, Anti-Duffy antigen, Anti-Fy glycoprotein, Anti-GpFy
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• reatividade de espécies: human, mouse, rat
• técnica(s): immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• nº de adesão NCBI: Q16570
• nº de adesão UniProt: Q16570
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... DARC(2532)

Descrição

Descrição geral

Duffy antigen/chemokine receptor (DARC) or atypical chemokine receptor 1 (ACKR1) is a membrane-bound protein. The gene encoding this chemokine receptor is localized on human chromosome 1q23.2.

Imunogênio

DARC antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human DARC.

Ações bioquímicas/fisiológicas

Duffy antigen/chemokine receptor (DARC) or atypical chemokine receptor 1 (ACKR1) functions as an antigen of the Duffy (Fy) blood group system. It has a role in the infection of red blood cells (RBCs) by Plasmodium vivax and the lysis of RBCs by Staphylococcus aureus. The protein has been shown to be downregulated in colorectal cancer.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Ligação

The action of this antibody can be blocked using blocking peptide SBP3500242.

forma física

Supplied in PBS with 0.02% sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable