S6324

Monoclonal Anti-SNX6 antibody produced in mouse

clone SNX6-76, ascites fluid, buffered aqueous solution

• Sinônimo(s): Anti-MSTP010, Anti-Sorting Nexin 6, Anti-TFAF2, Anti-Tumor necrosis factor receptor-associated factor 4(TRAF4)-associated factor 2
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 200
• conjugado: unconjugated
• forma do anticorpo: ascites fluid
• tipo de produto de anticorpo: primary antibodies
• clone: SNX6-76, monoclonal
• forma: buffered aqueous solution
• peso molecular: antigen ~47 kDa
• reatividade de espécies: mouse, human, bovine, rat
• embalagem: antibody small pack of 25 μL
• técnica(s): indirect ELISA: suitable; western blot: 1:2,500-1:5,000 using total extracts of A549 cells
• Isotipo: IgA
• nº de adesão UniProt: Q9UNH7
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... SNX6(58533) ; mouse ... Snx6(72183) ; rat ... Snx6(362738)

Descrição

Descrição geral

Monoclonal Anti-SNX6 (mouse IgA isotype) is derived from the hybridoma SNX6-76 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice.

SNX6 (sorting nexin 6) is a BACE1 (Β-site APP cleaving enzyme-1)-associated protein and a constituent of retromer. It belongs to the sorting nexin (SNX) family that has a PX (Phox homology) domain at its amino terminus and a BAR (Bin/amphiphysin/Rvc) domain at its carboxyl region. It is located on chromosome 14q13.

Aplicação

Monoclonal Anti-SNX6 antibody produced in mouse has been used in immunoblotting and ELISA.

Ações bioquímicas/fisiológicas

SNX6 (sorting nexin 6) helps in retrograde trafficking of the cation-independent mannose-6-phosphate receptor (CI-MPR) and sortilin. Interaction of SNX6 with breast cancer metastasis suppressor-1 induces transcriptional repression. It helps in the synthesis of lamin A and its transportation to the nuclear envelope .

forma física

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)