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RAB0705

Sigma-Aldrich

Human LTF / Lactotransferrin ELISA Kit

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About This Item

Código UNSPSC:
41116158
NACRES:
NA.32

reatividade de espécies

human

embalagem

kit of 96 wells (12 strips x 8 wells)

técnica(s)

ELISA: suitable

entrada

sample type cell culture supernatant(s)
sample type plasma
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1.96 ng/mL
standard curve range: 1.966-480 ng/mL

método de detecção

colorimetric

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

Informações sobre genes

human ... LTF(4057)

Descrição geral

LTF (lactotransferrin) codes for a 80 kDa glycoprotein which is expressed in many tissues and organs such as mammary gland, uterus, kidney and brain and found in body fluids including tears, milk, vitreous humor and saliva. Lactotransferrin is considered pleiotropic. Lactotransferrin belongs to the transferrin family and is homologous in sequence and structure with iron binding protein. The LTF gene is mapped to human chromosome 3p21.31.
The LTF ELISA kit provides for the Quantitative measurement of Lactotransferrin in Cell Culture Supernatants, Plasma and Serum.

Aplicação

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Ações bioquímicas/fisiológicas

Lactotransferrin regulates the immune and inflammatory responses. Lactotransferrin is also known to be involved in bone metabolism. It might play an important role in dental osseointegration implantation. Lactotransferrin is known for its antimicrobial anti-viral, anti-fungal, anti-parasitic, anti-inflammatory and antioxidant activity. Anti-angiogenic, anti-tumor effects of this protein proves that it is a tumor suppressor. Neuronal differentiation is also an important function of lactotransferrin.

Componentes do kit também disponíveis separadamente

Nº do produto
Descrição
SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

Pictogramas

Corrosion

Palavra indicadora

Warning

Frases de perigo

Declarações de precaução

Classificações de perigo

Met. Corr. 1

Código de classe de armazenamento

8A - Combustible corrosive hazardous materials

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Ming Wang et al.
Scientific reports, 7(1), 10733-10733 (2017-09-08)
Human lactoferrin (hLF) is a valuable protein for pharmaceutical products and functional foods, and worldwide demand for this protein has steadily increased. However, large-scale recombinant human lactoferrin (rhLF) production using current animal bioreactor techniques is limited by the low expression
Jocelyn R Grunwell et al.
Scientific reports, 9(1), 2874-2874 (2019-03-01)
Neutrophils are recruited to the airways of patients with acute respiratory distress syndrome (ARDS) where they acquire an activated pro-survival phenotype with an enhanced respiratory burst thought to contribute to ARDS pathophysiology. Our in vitro model enables blood neutrophil transepithelial
Katayi Mwila-Kazimbaya et al.
PloS one, 12(12), e0189351-e0189351 (2017-12-29)
Rotavirus vaccines have been introduced into national immunization programmes to mitigate morbidity and mortality associated rotavirus diarrhoea. Lower vaccine effectiveness has however been noted in low-middle income countries, but little is known about the role of maternal components found in
Ming-Tse Kuo et al.
International journal of molecular sciences, 22(1) (2021-01-07)
Most studies about dry eye disease (DED) chose unilateral eye for investigation and drew conclusions based on monocular results, whereas most studies involving tear proteomics were based on the results of pooling tears from a group of DED patients. Patients
Theresa J Ochoa et al.
The Journal of pediatrics, 219, 118-125 (2020-02-11)
To determine the effect of bovine lactoferrin on prevention of late-onset sepsis (LOS) and neurodevelopment delay. Randomized, double-blind, controlled trial in neonates with a birth weight of 500-2000 g in 3 neonatal units in Lima, Peru, comparing bovine lactoferrin 200 mg/kg/day

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