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PRS2301

Sigma-Aldrich

Anti-AIF antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Sinônimo(s):

Anti-Connector enhancer of kinase suppressor of Ras 1

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About This Item

Número MDL:
MFCD02685955
Código UNSPSC:
12352203
NACRES:
NA.41
conjugado:
unconjugated
application:
ELISA (i)
ICC
WB
clone:
polyclonal
reatividade de espécies:
mouse, human, rat
citations:
2
técnica(s):
immunocytochemistry: suitable
indirect ELISA: suitable
western blot: suitable

fonte biológica

rabbit

Nível de qualidade

100

conjugado

unconjugated

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

Formulário

buffered aqueous solution

peso molecular

predicted mol wt 67 kDa

reatividade de espécies

mouse, human, rat

técnica(s)

immunocytochemistry: suitable
indirect ELISA: suitable
western blot: suitable

nº de adesão UniProt

Q969H4

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... CNKSR1(10256)

Categorias relacionadas

Descrição geral

The previously assigned protein identifier O95381 has been merged into Q969H4. Full details can be found on the UniProt database.

Imunogênio

a peptide corresponding to amino acids 593-606 of human AIF. This sequence is identical to mouse and rat AIF.

Ligação

The action of this antibody can be blocked using blocking peptide SBP2301.

forma física

Solution in phosphate buffered saline containing 0.02% sodium azide

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Preços

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number
23010003D
2301-0003D

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Xiaowan Wang et al.
International journal of molecular sciences, 15(11), 20449-20468 (2014-11-12)
NAD+ is an essential co-enzyme for cellular energy metabolism and is also involved as a substrate for many cellular enzymatic reactions. It has been shown that NAD+ has a beneficial effect on neuronal survival and brain injury in in vitro
Xiaowan Wang et al.
Journal of neurochemistry, 151(6), 732-748 (2019-09-26)
NAD+ is a cofactor required for glycolysis, tricarboxylic acid cycle, and complex I enzymatic reaction. In mammalian cells, NAD+ is predominantly synthesized through the salvage pathway, where nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme. Previously, we demonstrated that NAMPT exerts
Roberta L Turner et al.
Virology, 456-457, 205-219 (2014-06-04)
Adenovirus inundates the productively infected cell with linear, double-stranded DNA and an abundance of single-stranded DNA. The cellular response to this stimulus is antagonized by the adenoviral E1B and E4 early genes. A mutant group C adenovirus that fails to
Dénes Nagy et al.
Archives of dermatological research, 306(10), 885-902 (2014-10-17)
TASK-3 (KCNK9 or K2P9.1) channels are thought to promote proliferation and/or survival of malignantly transformed cells, most likely by increasing their hypoxia tolerance. Based on our previous results that suggested mitochondrial expression of TASK-3 channels, we hypothesized that TASK-3 channels
Shengqiang Xu et al.
PloS one, 9(7), e100824-e100824 (2014-07-06)
Apoptosis-inducing factor (AIF) plays a crucial role in caspase-independent programmed cell death by triggering chromatin condensation and DNA fragmentation. Therefore, it might be involved in cell homeostasis and tumor development. In this study, we report significant AIF downregulation in the
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