P1306

Peptide YY human

≥97% (HPLC), synthetic

• Sinônimo(s): PYY, Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH₂
• Fórmula empírica (Notação de Hill): C₁₉₄H₂₉₅N₅₅O₅₇
• Número CAS: 118997-30-1
• Peso molecular: 4309.75
• Número MDL: MFCD00081843
• Código UNSPSC: 51111800
• NACRES: NA.32

Propriedades

• fonte biológica: synthetic
• Nível de qualidade: 200
• Ensaio: ≥97% (HPLC)
• forma: solid
• nº de adesão UniProt: P10082
• temperatura de armazenamento: −20°C
• Informações sobre genes: human ... PYY(5697)

Descrição

Amino Acid Sequence

Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2

Descrição geral

Human peptide YY (PYY) is secreted by mucosal L cells in the distal ileum, colon and rectum. It consists of 36 amino acids. The gene encoding PYY is localized on human chromosome 17q21.1.

Aplicação

Peptide YY human has been used as a supplement in Roswell Park Memorial Institute medium (RPMI medium) to culture pancreatic duct-derived cells.

Ações bioquímicas/fisiológicas

Gut hormone that inhibits both secretin and cholecystokinin-stimulated pancreatic secretion. Endogenous nonselective agonist at NPY receptors.

Human peptide YY (PYY) has a role in food ingestion, gut motility and insulin secretion. The protein suppresses appetite. It has been associated with obesity and type 2 diabetes. PYY also has a role in energy homeostasis.

Outras notas

Lyophilized from 0.1% TFA in H2O

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)