P0393

Protein Kinase Inhibitor from porcine heart

1-3 inhibitor U/μg protein, lyophilized powder

• Número MDL: MFCD00132115
• Código UNSPSC: 12352202

Propriedades

• fonte biológica: Porcine heart
• forma: lyophilized powder
• atividade específica: 1-3 inhibitor U/μg protein
• composição: Protein, ~50% biuret
• temperatura de armazenamento: 2-8°C

Descrição

Ações bioquímicas/fisiológicas

These proteins bind to the catalytic subunit of cyclic-AMP dependent protein kinase, displacing the regulatory subunit and inhibiting phosphorylating activity. The cyclic-AMP binding capacity of the regulatory subunit is enhanced. Many other proteins exhibit this enhancement ability, too (Brostrom, C.O. and Kon, C., Anal. Biochem., 58, 459 [1974]).

Embalagem

Package size based on protein content.

Definição da unidade

One unit will transfer 1.0 picomole (10^-12 mol) of phosphate from γ-³²P-ATP to hydrolyzed and partially dephosphorylated casein (Product No. C 4765) per min at pH 6.5 at 30 °C.

forma física

Supplied as lyophilized powder containing 30% glycerophosphate and 20% EDTA.

Nota de preparo

Fractionated essentially by procedure of Walsh, D.A., et al., J. Biol. Chem., 246, 1977 (1971).

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)