O7760

Okadaic acid sodium salt from Prorocentrum concavum

≥90% (HPLC), film

• Sinônimo(s): OA
• Fórmula empírica (Notação de Hill): C₄₄H₆₇NaO₁₃
• Número CAS: 209266-80-8
• Peso molecular: 826.98
• Número MDL: MFCD00210208
• Código UNSPSC: 12352106
• ID de substância PubChem: 329818921
• NACRES: NA.77

Propriedades

• fonte biológica: plant (Prorocentrum concavum)
• Nível de qualidade: 200
• Ensaio: ≥90% (HPLC)
• forma: film
• cor: translucent
• solubilidade: 0.1% acetic acid in CH₃CN: H₂O (1:1): 250 μg/mL, clear, colorless
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [Na+].C[C@@H]1CC[C@]2(CCCCO2)O[C@@H]1[C@@H](C)C[C@H](O)[C@H]3O[C@@H]4CC[C@@]5(CC[C@@H](O5)\C=C\[C@@H](C)[C@@H]6CC(C)=C[C@@]7(O[C@@H](CC[C@H]7O)C[C@@](C)(O)C([O-])=O)O6)O[C@H]4[C@H](O)C3=C
• InChI: 1S/C44H68O13.Na/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42;/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49);/q;+1/p-1/b10-9+;/t26-,27-,28+,30+,31+,32+,33-,34+,35-,36-,37+,38+,39-,41-,42+,43-,44-;/m1./s1
• chave InChI: BYHIFOCTDVNQQT-GHIYGBLASA-M

Descrição

Ações bioquímicas/fisiológicas

Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.

Características e benefícios

This compound is featured on the Phosphoprotein Phosphatases (Serine/Threonine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informações de segurança

• Pictogramas: GHS06
• Palavra indicadora: Danger
• Frases de perigo: H301 + H311 + H331,H315
• Declarações de precaução: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Classificações de perigo: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 3