MAK486

Carbonyl Assay Kit

sufficient for 100 colorimetric tests

• Código UNSPSC: 12161503

Propriedades

• Nível de qualidade: 100
• método de detecção: colorimetric
• doença(s) relevante(s): cardiovascular diseases; cancer; gastrointestinal diseases; aging/geriatric diseases; neurological disorders
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C

Descrição

Descrição geral

Carbonyl groups, such as ketones and aldehydes, are a common indicator of protein oxidation. Protein oxidation is caused because of exposure to reactive oxygen species (ROS) and is a common marker in various diseases, as well as aging.

Características e benefícios

• Linear detection range from 12 to 250 µM carbonyl
• Compatible with high-throughput handling systems.
• Convenient. The procedure involves adding a single working reagent, and reading the absorbance after 30 minutes.

Adequação

The kit is suitable for the quantification of carbonyl groups (e.g. ketones, aldehydes) or protein carbonyls in biological samples (e.g. oxidized BSA, etc.).

Princípio

The Carbonyl Assay Kit is based on an improved method, where 2,4-dinitrophenylhydrazine (DNPH) reacts with carbonyl groups to produce a colored compound at 375 nm. The intensity of this colored compound is directly proportional to the carbonyl groups in the sample.

Informações de segurança

• Pictogramas: GHS05
• Palavra indicadora: Warning
• Frases de perigo: H290
• Declarações de precaução: P234 - P390
• Classificações de perigo: Met. Corr. 1
• Código de classe de armazenamento: 8A - Combustible, corrosive hazardous materials
• Classe de risco de água (WGK): WGK 1