MAK484

Phenylalanine Assay Kit

sufficient for 100 fluorometric tests

• Sinônimo(s): Assay Kit for Phenylalanine Detection
• Código UNSPSC: 12161503
• NACRES: NA.84

Propriedades

• Nível de qualidade: 100
• método de detecção: fluorometric
• doença(s) relevante(s): metabolic disorders; neonatal diseases; pediatric diseases; neurological disorders
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C

Descrição

Descrição geral

Phenylalanine is an essential amino acid and an important precursor for several key signal molecules such as dopamine, norepinephrine, epinephrine, and the skin pigment melanin. It is found naturally in the breast milk of mammals and used as nutritional supplements in food and drink products. The genetic disorder phenylketonuria is the inability to metabolize phenylalanine. Individuals with this disorder are known as "phenylketonurics". Individuals who cannot metabolize phenylalanine must monitor their intake of protein to control the buildup of phenylalanine.

Características e benefícios

• The linear detection range of the kit is 2-300 µM L-phenylalanine
• Compatible with high-throughput handling systems.

Adequação

The kit is suitable for L-phenylalanine activity determination in serum, urine, and other biological samples.

Princípio

The Phenylalanine Assay Kit provides a convenient fluorometric means to measure L-phenylalanine in biological samples. In the assay, L-phenylalanine is oxidized by phenylalanine dehydrogenase, producing NADH, which reduces a fluorescent dye to a highly fluorescent product. The resulting fluorescence intensity at λEx = 530 nm/λEm = 585 nm is proportional to the L-phenylalanine concentration in the sample.

Informações de segurança

• Pictogramas: GHS08
• Palavra indicadora: Danger
• Frases de perigo: H334
• Declarações de precaução: P261 - P284 - P501
• Classificações de perigo: Resp. Sens. 1
• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2