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Merck
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Documentos Principais

M6546

Sigma-Aldrich

(±)-2-(p-Methoxyphenoxy)propionic acid

solid, ≥98%

Sinônimo(s):

PMP

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About This Item

Fórmula empírica (Notação de Hill):
C10H12O4
Número CAS:
Peso molecular:
196.20
Número MDL:
Código UNSPSC:
12352202
ID de substância PubChem:
NACRES:
NA.77

Nome do produto

(±)-2-(p-Methoxyphenoxy)propionic acid, ≥98%

fonte biológica

synthetic (organic)

Nível de qualidade

Ensaio

≥98%

Formulário

solid

cadeia de caracteres SMILES

COc1ccc(OC(C)C(O)=O)cc1

InChI

1S/C10H12O4/c1-7(10(11)12)14-9-5-3-8(13-2)4-6-9/h3-7H,1-2H3,(H,11,12)

chave InChI

MIEKOFWWHVOKQX-UHFFFAOYSA-N

Aplicação

(±)-2-(p-Methoxyphenoxy)propionic acid may be used as a sweet taste receptor antagonist to study its effect on allulose-induced glucagon-like peptide 1 (GLP-1) secretion rats. It may also be used to study the response of the secretin tumor cell line (STC-1) to sweetener in the presence and absence of (±)-2-(p-methoxyphenoxy)propionic acid or lactisole.

Ações bioquímicas/fisiológicas

As a taste modulator, the sodium salt inhibits the perception of sweetness in humans, but not in rats.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves


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A Sclafani et al.
Physiology & behavior, 61(1), 25-29 (1997-01-01)
Cypha, propionic acid, 2-(4-methoxyphenol) salt, is a commercially available sweet taste inhibitor used in food products. The present study examined whether or not Cypha blocked the sweet taste response of rats. This was accomplished by measuring the consummatory response of
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