M076000

Sulfur 42

• Sinônimo(s): Phenyl-3H-1,2,4-dithiazol-3-one
• Fórmula empírica (Notação de Hill): C₈H₅NOS₂
• Número CAS: 7047-10-1
• Peso molecular: 195.26
• Número MDL: MFCD02311276
• Código UNSPSC: 12352200
• ID de substância PubChem: 329817828
• NACRES: NA.03

Propriedades

• tipo: for DNA synthesis
• linha de produto: Proligo Reagents
• Ensaio: ≥99.0% (reversed phase HPLC)
• Formulário: solid
• embalagem: pkg of 1 g M076000-1G; 2 g of 2 g M076000-2G
• Impurezas: ≤0.1% water content (Karl Fischer)
• cor: faintly yellow to yellow
• solubilidade: acetonitrile: 0.1 M, clear
• adequação: conforms to structure for H-NMR
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: O=C1SSC(C2=CC=CC=C2)=N1
• InChI: 1S/C8H5NOS2/c10-8-9-7(11-12-8)6-4-2-1-3-5-6/h1-5H
• chave InChI: LKDWQHQNDDNHSC-UHFFFAOYSA-N

Descrição

Descrição geral

Sulfur 42 is a sulfurization reagent.

Aplicação

Sulfur 42 is suitable for use instead of an Oxidizer during the synthesis cycle to manufacture thioated oligonucleotides.

Características e benefícios

• Sulfur 42 is at least 4 times more reactive than Beaucage reagent or PADS
• Crystalline powder
• Odourless, no foul smell
• Solubility in ACN up to 0.28M at (+10 °C); no need to applied a co-solvent like in DCM, THF
• The solvent for the dissolution of the reagent should be dry (< 50 ppm) in order to minimize P=O impurities
• Stable in ACN solution for at least 21 days
• Recommended reaction time for the sulfurization in oligonucleotide synthesis for a 0.1M solution is 60 sec

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable