L6895
Lipid A, monophosphoryl from Salmonella enterica serotype minnesota Re 595 (Re mutant)
lyophilized powder, TLR ligand tested
Sinônimo(s):
Monophosphoryl Lipid A from Salmonella
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About This Item
Produtos recomendados
fonte biológica
Salmonella enterica (serotype minnesota Re 595 Re mutant)
Nível de qualidade
Formulário
lyophilized powder
Impurezas
<0.2% Ketodeoxyoctonate (KDO)
Condições de expedição
ambient
temperatura de armazenamento
2-8°C
Categorias relacionadas
Aplicação
Lipid A molecules compose the lipid membrane anchoring core components of endotoxins produced by Gram-negative bacteria. Lipid A molecules induce immune responses. Structually, lipid A molecules are composed of two glucosamine units with varied, species dependent, fatty acyl chain numbers and identity and degree of phosphorylation.
Lipid A, monophosphoryl from Salmonella enterica serotype minnesota Re 595 may be used in comparative assessment of the antigenicity of specific structures within different LPA molecules and analogues.
Lipid A, monophosphoryl from Salmonella enterica serotype minnesota Re 595 may be used in comparative assessment of the antigenicity of specific structures within different LPA molecules and analogues.
Ações bioquímicas/fisiológicas
Lipid A has immunostimulatory adjuvant activity including macrophage, T-cell, and B-cell activation. Research has shown Lipid A has greater Th1 than Th2 stimulation.
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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