L5288

Latrunculin B

from Latruncula magnifica, ≥80% (HPLC), solid, actin polymerization inhibitor

• Sinônimo(s): LAT-B
• Fórmula empírica (Notação de Hill): C₂₀H₂₉NSO₅
• Número CAS: 76343-94-7
• Peso molecular: 395.51
• Número MDL: MFCD00270879
• Código UNSPSC: 12352200
• ID de substância PubChem: 329817621
• NACRES: NA.77

Propriedades

• product name: Latrunculin B from Latruncula magnifica, ≥80% (HPLC), solid
• Nível de qualidade: 200
• Ensaio: ≥80% (HPLC)
• forma: solid
• peso molecular: 395.5
• solubilidade: ethanol: soluble
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: C[C@H]1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]3CSC(=O)N3)OC(=O)C=C(C)CCC=C1
• InChI: 1S/C20H29NO5S/c1-13-5-3-4-6-14(2)9-18(22)25-16-10-15(8-7-13)26-20(24,11-16)17-12-27-19(23)21-17/h3,5,9,13,15-17,24H,4,6-8,10-12H2,1-2H3,(H,21,23)/b5-3-,14-9-/t13-,15-,16-,17+,20-/m1/s1
• chave InChI: NSHPHXHGRHSMIK-JRIKCGFMSA-N

Descrição

Descrição geral

Latrunculin B is a macrocyclic toxin, which is produced by Latruncula magnifica.

Aplicação

Latrunculin B from Latruncula magnifica has been used for actin depolymerisation in various experiments. It has also been used as a component in bone marrow-derived dendritic cell (BMDC) complete medium, to study the formation of tubules from phagosomes in dendritic cells.

Ações bioquímicas/fisiológicas

Latrunculin B inhibits actin polymerization in vitro. Latrunculin B disrupts microfilament-mediated processes.

Outras notas

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)