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Key Documents

Outros documentos

H7909

Sigma-Aldrich

HU-210

solid (air sensitive)

Sinônimo(s):

(6aR-trans-3-(1, 1-Dimethylheptyl)-6a,7,10,10a-tetrahydro-1-hydroxy-6,6-dimethyl-6H-dibenzo[b,d]pyran-9-methanol

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About This Item

Fórmula empírica (Notação de Hill):
C25H38O3
Número CAS:
112830-95-2
Peso molecular:
386.57
Beilstein:
4298162
Número MDL:
MFCD01074786
Código UNSPSC:
12352200
ID de substância PubChem:
24895815
NACRES:
NA.77

forma

solid (air sensitive)

Nível de qualidade

100

controle de medicamentos

USDEA Schedule I; stupéfiant (France); regulated under CDSA - not available from Sigma-Aldrich Canada

condição de armazenamento

desiccated

solubilidade

DMSO: soluble

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[H][C@@]12CC(CO)=CC[C@@]1([H])C(C)(C)Oc3cc(cc(O)c23)C(C)(C)CCCCCC

InChI

1S/C25H38O3/c1-6-7-8-9-12-24(2,3)18-14-21(27)23-19-13-17(16-26)10-11-20(19)25(4,5)28-22(23)15-18/h10,14-15,19-20,26-27H,6-9,11-13,16H2,1-5H3/t19-,20-/m1/s1

chave InChI

SSQJFGMEZBFMNV-WOJBJXKFSA-N

Informações sobre genes

human ... CNR1(1268) , CNR2(1269)
rat ... Cnr1(25248)

Procurando produtos similares? Visita Guia de comparação de produtos

Ações bioquímicas/fisiológicas

Cannabinoid receptor agonist.

Características e benefícios

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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O Gomez et al.
British journal of pharmacology, 163(7), 1520-1532 (2011-04-13)
The endogenous cannabinoid system participates in oligodendrocyte progenitor differentiation in vitro. To determine the effect of synthetic cannabinoids on oligodendrocyte differentiation, we exposed differentiating cultures of oligodendrocytes with cannabinoid CB(1), CB(2) and CB(1)/CB(2) receptor agonists and antagonists. The response of
S E M Lewis et al.
International journal of andrology, 35(5), 731-740 (2012-03-23)
Recent societal acceptance of cannabinoids as recreational and therapeutic drugs has posed a potential hazard to male reproductive health. Mammals have a highly sophisticated endogenous cannabinoid (ECS) system that regulates male (and female) reproduction and exo-cannabinoids may influence it adversely.
A Ottani et al.
CNS drug reviews, 7(2), 131-145 (2001-07-28)
The synthetic compound HU 210 displays a multiplicity of biochemical, pharmacological, and behavioral effects, most of which have been demonstrated to be dependent on a selective agonistic activity at CB(1) and CB(2) cannabinoid receptors and to involve the main neurotransmitter
C L Limebeer et al.
British journal of pharmacology, 167(5), 1126-1136 (2012-06-08)
Conditioned gaping reactions reflect nausea-induced behaviour in rats. Cannabinoid 1 receptor (CB(1) ) agonists interfere with the establishment of nausea-induced conditioned gaping; however, it is not known if their effects are mediated by an action at peripheral or central CB(1)
Bob Roozenbeek et al.
Critical care medicine, 40(5), 1609-1617 (2012-04-19)
The International Mission on Prognosis and Analysis of Clinical Trials and Corticoid Randomisation After Significant Head injury prognostic models predict outcome after traumatic brain injury but have not been compared in large datasets. The objective of this is study is
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