H2779
HistoChoice® Clearing Agent
alternative to toluene and xylene
Sinônimo(s):
dewaxing mixture for paraffin tissue sections
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About This Item
Código UNSPSC:
12171500
NACRES:
NA.47
Produtos recomendados
Formulário
liquid
características do produto alternativo mais ecológico
Designing Safer Chemicals
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
cor
colorless
densidade
0.760-0.820 g/mL
aplicação(ões)
hematology
histology
categoria alternativa mais ecológica
, Aligned
temperatura de armazenamento
room temp
Descrição geral
HistoChoice® is a patented, complex mixture of agents that allow tissues to retain their structure, antigenic sites, and nucleic acid sites. It is a non-toxic, non-cross-linking fixative formulated to replace formaldehyde-based fixation. This formulation in non-citrus, contains no mercury, formaldehyde, or glutaraldehyde.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has Inherently Safer Chemistry, compared to the standard use of formalin for tissue processing.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has Inherently Safer Chemistry, compared to the standard use of formalin for tissue processing.
Aplicação
HistoChoice® Clearing Agent has the following applications:
- It is suitable as an alternative to toluene and xylene for dewaxing paraffin tissue sections. Prepared slides are suitable for antibody probing applications and in situ hybridizations.
- It has been employed in a study to explain the recalcitrance of lignocellulosic plant cell walls to enzymatic degradation.
- It has been used to develop a novel method to improve sensitivity for the localization of miRNA and their target transcripts in plants.
- It has been used to study the correlation of cytoplasmic ADP-ribosylation levels with markers of patient outcome in human cancers.
Ações bioquímicas/fisiológicas
Fixation with HistoChoice® works well in immunohistology applications where its non-cross-linking traits are conducive to epitope retrieval and identification by primary antibodies to extracellular matrix components.
Características e benefícios
- Non-toxic, non-carcinogenic, and odorless.
- Non-flammable.
- Preserves native antigenic and nucleic acid sites.
- Compatible with many organic mounting media.
- Dissolves wax faster and evaporates slower than xylene.
- Can be used in automated processors.
- Tissues retain their original structure.
Informações legais
HistoChoice is a registered trademark of Amresco, Inc.
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Órgãos-alvo
Respiratory system
Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
142.0 °F
Ponto de fulgor (°C)
61.1 °C
Equipamento de proteção individual
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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