H135
5-Hydroxydecanoic acid sodium salt
≥97% (HPLC)
Sinônimo(s):
5-hydroxydecanoate sodium salt
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About This Item
Produtos recomendados
Nível de qualidade
Ensaio
≥97% (HPLC)
Formulário
powder
condição de armazenamento
desiccated
cor
white to beige
solubilidade
H2O: 10 mg/mL, clear
cadeia de caracteres SMILES
[Na+].CCCCCC(O)CCCC([O-])=O
InChI
1S/C10H20O3.Na/c1-2-3-4-6-9(11)7-5-8-10(12)13;/h9,11H,2-8H2,1H3,(H,12,13);/q;+1/p-1
chave InChI
YNAGNECWEKMWRM-UHFFFAOYSA-M
Ações bioquímicas/fisiológicas
Blocks post-ischemic actions of the K+ channel activator cromakalim.
Características e benefícios
This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Atenção
Hygroscopic
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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Cardiology, 123(3), 177-180 (2012-11-07)
We investigated whether ischemic preconditioning (IPC) protects the right ventricular (RV) myocardium against ischemic injury in hearts treated with the specific mitochondrial ATP-sensitive potassium (K(ATP)) channel blocker 5-hydroxydecanoate (5-HD). Hearts from male Wistar rats (300 g, n = 39) were
Ischemic preconditioning of the right ventricle: a new application for an old concept?.
Cardiology, 123(3), 175-176 (2012-11-07)
Chinese medicine, 6(1), 7-7 (2011-02-16)
Danshen-Gegen decoction (DG), a Chinese herbal formula, has been demonstrated to be effective for the treatment of coronary heart disease such as myocardial infarction. In the present study, we investigated the effect of DG post-conditioning on isoproterenol (ISO)-induced myocardial injury
Pharmacology, 90(1-2), 110-116 (2012-07-21)
Eribis peptide 94 (EP 94) is a new enkephalin derivative which potently binds to the µ- and δ-opioid receptor. In this study, we determined the effects of EP 94 and potential mechanism(s) involved in cardioprotection of the rat heart. An
Ischemia reperfusion injury, KATP channels, and exercise-induced cardioprotection against apoptosis.
Journal of applied physiology (Bethesda, Md. : 1985), 113(3), 498-506 (2012-06-02)
Exercise is a potent stimulus against cardiac ischemia reperfusion (IR) injury, although the protective mechanisms are not completely understood. The study purpose was to examine whether the mitochondrial or sarcolemmal ATP-sensitive potassium channel (mito K(ATP) or sarc K(ATP), respectively) mediates
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