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Key Documents

D8768

Sigma-Aldrich

cis-4,7,10,13,16,19-Docosahexaenoic acid sodium salt

≥95%, waxy solid

Sinônimo(s):

Sodium (all-Z)-4,7,10,13,16,19-docosahexaenoate

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About This Item

Fórmula linear:
C22H31O2Na
Número CAS:
Peso molecular:
350.47
Código UNSPSC:
12352211
ID de substância PubChem:
NACRES:
NA.25

fonte biológica

cod liver oil

Nível de qualidade

Ensaio

≥95%

forma

waxy solid

grupo funcional

carboxylic acid

tipo de lipídio

omega FAs

Condições de expedição

ambient

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(O[Na])=O

InChI

1S/C22H32O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24;/h3-4,6-7,9-10,12-13,15-16,18-19H,2,5,8,11,14,17,20-21H2,1H3,(H,23,24);/q;+1/p-1/b4-3-,7-6-,10-9-,13-12-,16-15-,19-18-;

chave InChI

SNNDEWVSGZRIFE-FPYKSTABSA-M

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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Christel Björk et al.
Nutrition & metabolism, 13, 4-4 (2016-01-21)
Previous studies suggest that intake of specific bioactive compounds may have beneficial clinical effects on adipose tissue partly due to their anti-inflammatory and insulin-sensitizing properties. With the overall aim to contribute to better understanding of the mechanisms of selected bioactive
Wei Cai et al.
Translational stroke research, 9(6), 669-680 (2018-09-12)
Systemic docosahexaenoic acid (DHA) has been explored as a clinically feasible protectant in stroke models. However, the mechanism for DHA-afforded neuroprotection remains elusive. Transient middle cerebral artery occlusion (tMCAO) was induced for 1 h. DHA (i.p., 10 mg/kg) was administered immediately after
Shurong Huang et al.
Journal of lipid research, 53(9), 2002-2013 (2012-07-07)
Toll-like receptor 4 (TLR4) and TLR2 were shown to be activated by saturated fatty acids (SFAs) but inhibited by docosahexaenoic acid (DHA). However, one report suggested that SFA-induced TLR activation in cell culture systems is due to contaminants in BSA
Yong-Ping Zhang et al.
Prostaglandins, leukotrienes, and essential fatty acids, 136, 85-94 (2017-08-06)
Omega-3 polyunsaturated fatty acids (n-3 PUFAs), docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), have been reported to prevent neurodegenerative diseases such as Alzheimer's disease (AD) in both experimental and clinical/epidemiological studies. However, whether DHA and EPA from natural products exert
Ryan G Snodgrass et al.
Journal of immunology (Baltimore, Md. : 1950), 191(8), 4337-4347 (2013-09-18)
Many studies have shown that TLR4- and TLR2-deficient mice are protected from high-fat diet-induced inflammation and insulin resistance, suggesting that saturated fatty acids derived from the high-fat diet activate TLR-mediated proinflammatory signaling pathways and induce insulin resistance. However, evidence that

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