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D4288

Sigma-Aldrich

Digalacturonic acid

≥85% (HPLC)

Sinônimo(s):

α-D-GalA-(1→4)-D-GalA

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About This Item

Fórmula empírica (Notação de Hill):
C12H18O13
Número CAS:
5894-59-7
Peso molecular:
370.26
Número MDL:
MFCD00079142
Código UNSPSC:
12352201
ID de substância PubChem:
24893853
NACRES:
NA.25

fonte biológica

synthetic (organic)

Nível de qualidade

200

Ensaio

≥85% (HPLC)

forma

powder

cor

white to off-white

solubilidade

water: 50 mg/mL, clear, colorless to faintly yellow

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

OC(C=O)C(O)C(OC1OC(C(O)C(O)C1O)C(O)=O)C(O)C(O)=O

InChI

1S/C12H18O13/c13-1-2(14)3(15)8(7(19)10(20)21)24-12-6(18)4(16)5(17)9(25-12)11(22)23/h1-9,12,14-19H,(H,20,21)(H,22,23)

chave InChI

SYBQLSSECRIKMJ-UHFFFAOYSA-N

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Aplicação

Digalacturonic acid (DGA), derived in vivo from pectin catabolism, is used for the co-crystallization of enzymes such as proteinase K. It is used in galacturonic acid metabolism research as a substrate to identify, differentiate and characterized endo- and exopolygalacturonase(s) and gluconase(s). DGA is used to study the transport of oligogalacturonides by systems such as the TogMNAB ABC transporter.

Outras notas

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

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Lisha Zhang et al.
Fungal genetics and biology : FG & B, 48(10), 990-997 (2011-06-21)
D-galacturonic acid is the most abundant component of pectin, one of the major polysaccharide constituents of plant cell walls. Galacturonic acid potentially is an important carbon source for microorganisms living on (decaying) plant material. A catabolic pathway was proposed in
V E Miamin et al.
Genetika, 40(9), 1187-1193 (2004-11-24)
A mutant that cannot utilize pectin substances of plant cell walls was obtained via insertion of mini-mini-Tn5xylE transposon into the chromosome of phytopathogenic bacteria Erwinia carotovora subsp. atroseptica. The inability of mutant cells to utilize these substrates was caused by
V Valmeekam et al.
Molecular plant-microbe interactions : MPMI, 14(6), 816-820 (2001-06-02)
The negative regulatory protein ExuR in Erwinia chrysanthemi regulates expression of the galacturonate uptake (exuT) and utilization (uxaA, uxaB, uxaC) genes. We cloned and determined the nucleotide sequence of the exuR gene from E. chrysanthemi EC16. Analysis of the deduced
N Hugouvieux-Cotte-Pattat et al.
Molecular microbiology, 41(5), 1113-1123 (2001-09-14)
The bacterium Erwinia chrysanthemi, which causes soft rot disease on various plants, is able to use pectin as a carbon source for growth. Knowledge of the critical step in pectin catabolism which allows the entry of pectic oligomers into the
S Gognies et al.
Journal of industrial microbiology & biotechnology, 39(7), 1023-1029 (2012-03-01)
In Saccharomyces cerevisiae, an endopolygalacturonase encoded by the PGL1 gene catalyzes the random hydrolysis of the α-1,4 glycosidic linkages in polygalacturonic acid. To study the regulation of the PGL1 gene, we constructed a reporter vector containing the lacZ gene under
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