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D2779

Sigma-Aldrich

Dimethyldioctadecylammonium bromide

≥98% (TLC)

Sinônimo(s):

Distearyldimethylammonium bromide

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About This Item

Fórmula linear:
[CH3(CH2)17]2N(Br)(CH3)2
Número CAS:
3700-67-2
Peso molecular:
630.95
Beilstein:
3580323
Número CE:
223-037-6
Número MDL:
MFCD00041975
Código UNSPSC:
12161900
ID de substância PubChem:
24893713
NACRES:
NA.25

descrição

cationic

Nível de qualidade

200

Ensaio

≥98% (TLC)

forma

powder

peso molecular

630.95 g/mol

pf

~160 °C

aplicação(ões)

cell analysis

cadeia de caracteres SMILES

CCCCCCCCCCCCCCCCCC[N+](CCCCCCCCCCCCCCCCCC)(C)C.[Br-]

InChI

1S/C38H80N.BrH/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-39(3,4)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2;/h5-38H2,1-4H3;1H/q+1;/p-1

chave InChI

PSLWZOIUBRXAQW-UHFFFAOYSA-M

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Descrição geral

Dimethyldioctadecylammonium bromide is a cationic lipid that stimulates immune responses, activates macrophages, and binds to antigens.

Aplicação

Dimethyldioctadecylammonium bromide has been used in a study to assess the interaction of its monolayers with DNA using specular neutron reflection, surface pressure-area isotherms, and Brewster angle microscopy. It has also been used in a study to investigate new adjuvants for use in kill vaccines for bovine viral diarrhea virus (BVDV).

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Sigma-Aldrich

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Benzyldodecyldimethylammonium bromide

Sigma-Aldrich

B5776

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2′,3′-Dideoxyadenosine ≥97% (HPLC)

Sigma-Aldrich

D1285

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Julia F Ridpath et al.
Veterinary research communications, 34(8), 691-702 (2010-09-28)
Bovine viral diarrhea virus (BVDV) infections cause respiratory, reproductive, and enteric disease in cattle. Vaccination raises herd resistance and limits the spread of BVDV among cattle. Both killed and modified live vaccines against BVDV are available. While modified live vaccines
F S Baechtel et al.
Cancer research, 42(12), 4959-4963 (1982-12-01)
Dimethyldioctadecylammonium bromide (DDA) stimulates immune responses, primes (or activates) macrophages, and binds to antigens. Because relatively little is known about the binding of adjuvants to antigens, the nature of the interaction of DDA with soluble protein and cellular antigens was
Mette Hamborg et al.
Pharmaceutical research, 30(1), 140-155 (2012-09-08)
Understanding the nature of adjuvant-antigen interactions is important for the future design of efficient and safe subunit vaccines, but remains an analytical challenge. We studied the interactions between three model protein antigens and the clinically tested cationic liposomal adjuvant composed
Eloi Feitosa et al.
PloS one, 7(9), e44702-e44702 (2012-09-13)
Dioctadecyldimethylammonium bromide (DODAB) is a double chain cationic lipid, which assembles as bilayer structures in aqueous solution. The precise structures formed depend on, e.g., lipid concentration and temperature. We here combine differential scanning calorimetry (DSC) and X-ray scattering (SAXS and
Agnes Michanek et al.
Langmuir : the ACS journal of surfaces and colloids, 28(25), 9621-9633 (2012-05-26)
The objective of this work is to establish under which conditions short RNA molecules (similar to miRNA) associate with zwitterionic phospholipids and how this differs from the association with cationic surfactants. We study how the base pairing (i.e., single stranded
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